Gene

ddx18

ID
ZDB-GENE-030131-9685
Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
Symbol
ddx18 Nomenclature History
Previous Names
  • cb155 (1)
  • fa19d11
  • sb:cb155
  • wu:fa19d11 (1)
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have ATP binding activity; RNA binding activity; and RNA helicase activity. Involved in myeloid cell differentiation. Predicted to localize to nucleolus. Is expressed in several structures, including alar plate midbrain region; digestive system; intermediate cell mass of mesoderm; nervous system; and trunk vasculature. Orthologous to human DDX18 (DEAD-box helicase 18).
Genome Resources
Note
None
Expression
All Expression Data
9 figures from 4 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
10 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ddx18 Human Ortholog
No data available
Associated With ddx18 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site
Domain IPR001650 Helicase, C-terminal
Domain IPR011545 DEAD/DEAH box helicase domain
Domain IPR014001 Helicase superfamily 1/2, ATP-binding domain
Domain IPR014014 RNA helicase, DEAD-box type, Q motif
Domain IPR025313 Domain of unknown function DUF4217
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length ATP-dependent RNA helicase DEAD-box, conserved site DEAD/DEAH box helicase domain Domain of unknown function DUF4217 Helicase, C-terminal Helicase superfamily 1/2, ATP-binding domain P-loop containing nucleoside triphosphate hydrolase RNA helicase, DEAD-box type, Q motif
UniProtKB:Q6DRL1 653
UniProtKB:Q4V9K8 653
UniProtKB:F1QLW8 653
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-ddx18 polyclonal IgG Rabbit
Bethyl Laboratories, Inc.
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations