ZFIN ID: ZDB-GENE-020509-2
Gene Name: gastrulation brain homeobox 2
Gene Symbol: gbx2
Previous Names: gbx-2 (1), fd07f12, wu:fd07f12 (1)
Location: Chr: 6 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 25 figures from 15 publications
Directly Submitted Expression Data: 10 figures (39 images) from Rhinn et al., 2003 [mb2]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Long-pec (48.0h-60.0h)
  anatomical structure, caudal fin, cerebellum, diencephalon (all 22) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
e30 Point Mutation Unknown Unknown ENU
fh248 Point Mutation Unknown Unknown ENU
fh253 Point Mutation Unknown Unknown
  • Zebrafish International Resource Center (ZIRC) (order this)
  • China Zebrafish Resource Center (CZRC) (order this)
  • gbx2_unrecovered Point Mutation Unknown Unknown ENU
    sa40660 Point Mutation Unknown Unknown ENU
    Targeting reagents: MO1-gbx2 (1)
    PHENOTYPE
    Data: 4 figures from Burroughs-Garcia et al., 2011
    Observed in: cell proliferation in forebrain, cell proliferation in hindbrain, cranial nerve V motor neuron, cranial nerve V neuronal cell body (all 10) expand
    DISEASE ASSOCIATED WITH gbx2 HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cerebellum development (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR020479 (1)
  • InterPro:IPR031250 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA gbx2-001 (1) 2095
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM gbx2
    Tg(hsp70l:gbx2), Tg1(gbx2-hsp70l:EGFP), Tg2(gbx2-hsp70l:EGFP), Tg3(gbx2-hsp70l:EGFP), Tg4(gbx2-hsp70l:EGFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    gbx2Contained in: [BAC] DKEY-30F11 (1) (order this)
    gbx2Encodes: [EST] fd07f12 (1), mb2 (1)
    [cDNA] MGC:73023 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_152964 (1) 2113bp
    Genomic GenBank:CR847983 (1) 199111bp
    Select Tool
    Polypeptide UniProtKB:Q8AXK9 (1) 342aa
    Sequence Clusters UniGene:17548 (1)
    Sequence Information (all 18)
    OTHER gbx2 GENE PAGES
  • Gene:245948 (1)
  • VEGA:OTTDARG00000034418 (1)
  • Ensembl(GRCz10):ENSDARG00000002933 (1)
  • ORTHOLOGY for gbx2 (Chr: 6)
    Species Symbol Chromosome Accession # Evidence
    Human GBX2 2
  • Gene:2637
  • OMIM:601135
  • HGNC:4186
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (2)
    Mouse Gbx2 1
  • MGI:95668
  • Gene:14472
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (44)