Gene

ckbb

ID

ZDB-GENE-020103-2

Name

creatine kinase, brain b

Symbol

ckbb Nomenclature History

Previous Names

ckb (1)
bck (1)
cb594 (1)
wu:fj36f10 (1)
wu:fj37d11 (1)

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to enable creatine kinase activity. Predicted to be involved in phosphocreatine biosynthetic process. Predicted to act upstream of or within phosphorylation. Predicted to be active in extracellular space. Is expressed in several structures, including fin bud; nervous system; neural tube; prechordal plate; and trigeminal placode. Orthologous to human CKB (creatine kinase B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

13 figures from 7 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb594 (17 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ckbb Human Ortholog

No data available

Associated With ckbb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR022415	ATP:guanido phosphotransferase active site
Domain	IPR022413	ATP:guanido phosphotransferase, N-terminal
Domain	IPR022414	ATP:guanido phosphotransferase, catalytic domain
Family	IPR000749	ATP:guanido phosphotransferase
Homologous_superfamily	IPR014746	Glutamine synthetase/guanido kinase, catalytic domain
Homologous_superfamily	IPR036802	ATP:guanido phosphotransferase, N-terminal domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length	ATP:guanido phosphotransferase	ATP:guanido phosphotransferase active site	ATP:guanido phosphotransferase, catalytic domain	ATP:guanido phosphotransferase, N-terminal	ATP:guanido phosphotransferase, N-terminal domain superfamily	Glutamine synthetase/guanido kinase, catalytic domain
UniProtKB:Q8AY63	InterPro	381

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	ckbb-203 (1) Ensembl	Ensembl	733 nt	Select Tool ZFIN BLAST
aberrant processed transcript	ckbb-205 (1) Ensembl	Ensembl	791 nt	Select Tool ZFIN BLAST
mRNA	ckbb-201 (1) Ensembl	Ensembl	1,464 nt	Select Tool ZFIN BLAST
mRNA	ckbb-204 (1) Ensembl	Ensembl	881 nt	Select Tool ZFIN BLAST
mRNA	ckbb-207 (1) Ensembl	Ensembl	861 nt	Select Tool ZFIN BLAST
ncRNA	ckbb-004 (1) Ensembl	Ensembl	597 nt	Select Tool ZFIN BLAST
ncRNA	ckbb-005 (1) Ensembl	Ensembl	947 nt	Select Tool ZFIN BLAST
ncRNA	ckbb-006 (1) Ensembl	Ensembl	516 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations