ZFIN ID: ZDB-GENE-011219-1
Gene Name: cytochrome P450, family 1, subfamily A
Gene Symbol: cyp1a
Previous Names: cyp1a1 (1), zfCYP1A, wu:fb63b04 (1), zgc:109747
Location: Chr: 18   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 82 figures from 37 publications
Directly Submitted Expression Data: 6 figures (13 images) from Thisse et al., 2004 [IMAGE:7163229]
Wild-type Stages, Structures: Blastula:Sphere (4.0h-4.33h) to Adult (90d-730d, breeding adult)
  apical ectodermal ridge pectoral fin bud, artery, blood vessel endothelial cell, brain (all 34) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la027978Tg, sa17179
Knockdown reagents: MO1-cyp1a (1), MO2-cyp1a (1)
PHENOTYPE No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cellular aromatic compound metabolic process (more)
Cellular Component endoplasmic reticulum (more)
Molecular Function aromatase activity (more)
GO Terms (all 16)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001128 (1)
  • InterPro:IPR002401 (1)
  • InterPro:IPR008066 (1)
  • InterPro:IPR017972 (1)
  • PROSITE:PS00086 (1)
  • Pfam:PF00067 (1)
  • EC:1.14.14.1 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cyp1a-001 (1) 2608
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    Ab1-cyp1a (1)
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cyp1a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    cyp1a Contained in: [Fosmid] CH1073-392K22 (1) (order this)
    cyp1a Encodes: [EST] fb63b04 (1), IMAGE:7163229 (1) (order this)
    [cDNA] MGC:109747 (1) (order this), MGC:193050 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131879 (1) 2610 bp
    Genomic GenBank:CU462829 (1) 31938 bp
    Select Tool
    Polypeptide UniProtKB:Q6TH23 (1) 519 aa
    Sequence Clusters UniGene:105078 (1)
    Sequence Information (all 27)
    OTHER cyp1a GENE PAGES
  • Gene:140634 (1)
  • VEGA:OTTDARG00000032407 (1)
  • Ensembl(Zv9):ENSDARG00000026039 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA NT CL
    Zebrafish cyp1a 18  
    Human CYP1A1 15 (15q24.1)
  • OMIM:108330
  • Gene:1543
  • Orthology Details
    CITATIONS (133)