Gene

cldne

ID
ZDB-GENE-010328-5
Name
claudin e
Symbol
cldne Nomenclature History
Previous Names
  • cb84 (1)
  • cldn28a (1)
  • fb16e12
  • wu:fb16e12 (1)
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to have structural molecule activity. Involved in epiboly involved in gastrulation with mouth forming second. Predicted to localize to bicellular tight junction; integral component of membrane; and plasma membrane. Human ortholog(s) of this gene implicated in ovarian cancer and pancreatic cancer. Is expressed in several structures, including EVL; blastomere; digestive system; ectoderm; and pleuroperitoneal region. Orthologous to several human genes including CLDN4 (claudin 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
25 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from Siddiqui et al., 2010
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cldne Human Ortholog
No data available
Associated With cldne Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017974 Claudin, conserved site
Family IPR005411 Claudin-2
Family IPR006187 Claudin
Domain Details Per Protein
Protein Length Claudin Claudin-2 Claudin, conserved site
UniProtKB:Q90XR9 209
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations