ZFIN ID: ZDB-GENE-030131-7190
Gene Name: methyl CpG binding protein 2
Gene Symbol: mecp2
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function DNA binding IEA InterPro:IPR001739 ZFIN Electronic Annotation
DNA binding IEA InterPro:IPR016177 ZFIN Electronic Annotation
DNA binding IEA UniProtKB-KW:KW-0238 ZFIN Electronic Annotation
DNA-binding transcription factor activity IDA Leong et al., 2015
double-stranded methylated DNA binding IBA PANTHER:PTN000424568 Gaudet et al., 2010
double-stranded methylated DNA binding IEA UniRule:UR000436755 UniProt curators
double-stranded methylated DNA binding IEA InterPro:IPR017353 ZFIN Electronic Annotation
methyl-CpG binding IBA PANTHER:PTN000424568 Gaudet et al., 2010
Cellular Component cytosol IBA PANTHER:PTN000424568 Gaudet et al., 2010
heterochromatin IBA PANTHER:PTN000424568 Gaudet et al., 2010
nucleus IBA PANTHER:PTN001431162 Gaudet et al., 2010
nucleus IEA InterPro:IPR001739 ZFIN Electronic Annotation
nucleus IEA InterPro:IPR017353 ZFIN Electronic Annotation
nucleus IEA UniProtKB-KW:KW-0539 ZFIN Electronic Annotation
Biological Process axon development IMP MO3-mecp2 Nozawa et al., 2017
axon development IMP MO4-mecp2 Nozawa et al., 2017
axonogenesis involved in innervation IGI robo2, MO5-mecp2 Leong et al., 2015
axonogenesis involved in innervation IGI sema5ba, MO5-mecp2 Leong et al., 2015
axonogenesis involved in innervation IMP MO5-mecp2 Leong et al., 2015
axonogenesis involved in innervation IMP mecp2fh232/fh232 Leong et al., 2015
inflammatory response IMP mecp2fh232/fh232 van der Vaart et al., 2017
locomotory behavior IMP mecp2fh232/fh232 (AB) Pietri et al., 2013
negative regulation of transcription by RNA polymerase II IBA PANTHER:PTN000424568 Gaudet et al., 2010
negative regulation of transcription by RNA polymerase II IEA UniRule:UR000436755 UniProt curators
negative regulation of transcription by RNA polymerase II IEA InterPro:IPR017353 ZFIN Electronic Annotation
neuromuscular junction development IMP MO3-mecp2 Nozawa et al., 2017
neuromuscular junction development IMP MO4-mecp2 Nozawa et al., 2017
presynapse assembly IGI MO1-bdnf, MO3-mecp2 Nozawa et al., 2017
regulation of neuron differentiation IGI MO1-id1, MO2-mecp2 Gao et al., 2015
regulation of neuron differentiation IGI MO3-her2, MO2-mecp2 Gao et al., 2015
regulation of neuron differentiation IMP CRISPR1-mecp2 Gao et al., 2015
regulation of neuron differentiation IMP MO2-mecp2 Gao et al., 2015
response to radiation IBA PANTHER:PTN000386636 Gaudet et al., 2010
sensory perception of touch IGI robo2, MO5-mecp2 Leong et al., 2015
sensory perception of touch IGI sema5ba, MO5-mecp2 Leong et al., 2015