ZFIN

ZFIN ID: ZDB-TGCONSTRCT-080207-1

ZFIN ID: ZDB-TGCONSTRCT-080207-1

CITATIONS (48 total)

Transgenic Construct Name:	Tg(krt4:GFP)
Transgenic Construct Symbol:	Tg(krt4:GFP)

Maili, L., Tandon, B., Yuan, Q., Menezes, S., Chiu, F., Hashmi, S.S., Letra, A., Eisenhoffer, G.T., Hecht, J.T. (2023) Disruption of fos causes craniofacial anomalies in developing zebrafish. Frontiers in cell and developmental biology. 11:11418931141893

Li, Y., Lee, A.Q., Lu, Z., Sun, Y., Lu, J.W., Ren, Z., Zhang, N., Liu, D., Gong, Z. (2022) Systematic Characterization of the Disruption of Intestine during Liver Tumor Progression in the xmrk Oncogene Transgenic Zebrafish Model. Cells. 11(11)

Monroe, J.D., Fraher, D., Huang, X., Mellett, N.A., Meikle, P.J., Sinclair, A.J., Lirette, S.T., Maihle, N.J., Gong, Z., Gibert, Y. (2022) Identification of novel lipid biomarkers in xmrk- and Myc-induced models of hepatocellular carcinoma in zebrafish. Cancer & metabolism. 10:7

Yu, Y., Alvarado, R., Petty, L.E., Bohlender, R.J., Shaw, D.M., Below, J.E., Bejar, N., Ruiz, O.E., Tandon, B., Eisenhoffer, G.T., Kiss, D.L., Huff, C.D., Letra, A., Hecht, J.T. (2022) Polygenic risk impacts PDGFRA mutation penetrance in nonsyndromic cleft lip and palate. Human molecular genetics. 31(14):2348-2357

Hatzold, J., Wessendorf, H., Pogoda, H.M., Bloch, W., Hammerschmidt, M. (2021) The Kunitz-type serine protease inhibitor Spint2 is required for cellular cohesion, coordinated cell migration and cell survival during zebrafish hatching gland development. Developmental Biology. 476:148-170

Lu, J.W., Sun, Y., Lin, L.I., Liu, D., Gong, Z. (2021) Exacerbation of Liver Tumor Metastasis in twist1a+/xmrk+ Double Transgenic Zebrafish following Lipopolysaccharide or Dextran Sulphate Sodium Exposure. Pharmaceuticals (Basel, Switzerland). 14(9):

Wurster, S., Ruiz, O.E., Samms, K.M., Tatara, A.M., Albert, N.D., Kahan, P.H., Nguyen, A.T., Mikos, A.G., Kontoyiannis, D.P., Eisenhoffer, G.T. (2021) EGF-mediated suppression of cell extrusion during mucosal damage attenuates opportunistic fungal invasion. Cell Reports. 34:108896

Armistead, J., Hatzold, J., van Roye, A., Fahle, E., Hammerschmidt, M. (2020) Entosis and apical cell extrusion constitute a tumor-suppressive mechanism downstream of Matriptase. The Journal of cell biology. 219(2):

Fei, F., Sun, S., Li, Q., Pei, Z., Wang, L., Zhang, R., Luo, F., Yu, M., Wang, X. (2020) Combinatorial normalization of liver-derived cytokine pathways alleviates hepatic tumor-associated cachexia in zebrafish. Cancer research. 81(4):873-884

Golenberg, N., Squirrell, J.M., Bennin, D.A., Rindy, J., Pistono, P.E., Eliceiri, K.W., Shelef, M.A., Kang, J., Huttenlocher, A. (2020) Citrullination regulates wound responses and tissue regeneration in zebrafish. The Journal of cell biology. 219(4):

Liu, H., Duncan, K., Helverson, A., Kumari, P., Mumm, C., Xiao, Y., Carlson, J.C., Darbellay, F., Visel, A., Leslie, E., Breheny, P., Erives, A.J., Cornell, R.A. (2020) Analysis of zebrafish periderm enhancers facilitates identification of a regulatory variant near human KRT8/18. eLIFE. 9:

Oralová, V., Rosa, J.T., Larionova, D., Witten, P.E., Huysseune, A. (2020) Multiple epithelia are required to develop teeth deep inside the pharynx. Proceedings of the National Academy of Sciences of the United States of America. 117(21):11503-11512

Fei, F., Wang, L., Sun, S., Lv, K., Yao, Y., Wang, J., Yu, M., Wang, X. (2019) Transgenic Strategies to Generate Heterogeneous Hepatic Cancer Models in Zebrafish. Journal of molecular cell biology. 11(11):1021-1023

Li, H., Lu, J.W., Huo, X., Li, Y., Li, Z., Gong, Z. (2019) Effects of sex hormones on liver tumor progression and regression in Myc/xmrk double oncogene transgenic zebrafish. General and comparative endocrinology. 277:112-121

Li, Y., Agrawal, I., Gong, Z. (2019) Reversion of tumor hepatocytes to normal hepatocytes during liver tumor regression in an oncogene transgenic zebrafish model. Disease models & mechanisms. 12(10):

Nakayama, J., Lu, J.W., Makinoshima, H., Gong, Z. (2019) A novel zebrafish model of metastasis identifies the HSD11β1 inhibitor Adrenosterone as a suppressor of epithelial-mesenchymal transition and metastatic dissemination. Molecular cancer research : MCR. 18(3):477-487

Oralová, V., Rosa, J.T., Soenens, M., Bek, J.W., Willaert, A., Witten, P.E., Huysseune, A. (2019) Beyond the whole-mount phenotype: high-resolution imaging in fluorescence-based applications on zebrafish. Biology Open. 8(5):

Teixeira Rosa, J., Oralová, V., Larionova, D., Eisenhoffer, G.T., Eckhard Witten, P., Huysseune, A. (2019) Periderm invasion contributes to epithelial formation in the teleost pharynx. Scientific Reports. 9:10082

van den Berg, M.C.W., MacCarthy-Morrogh, L., Carter, D., Morris, J., Ribeiro Bravo, I., Feng, Y., Martin, P. (2019) Proteolytic and Opportunistic Breaching of the Basement Membrane Zone by Immune Cells during Tumor Initiation. Cell Reports. 27:2837-2846.e4

Wang, J., Fei, F., Berberoglu, M.A., Sun, S., Wang, L., Dong, Z., Wang, X. (2018) Csy4-based vector system enables conditional chimeric gene editing in zebrafish without interrupting embryogenesis. Journal of molecular cell biology. 10(6):586-588

Yao, Y., Sun, S., Wang, J., Fei, F., Dong, Z., Ke, A.W., He, R., Wang, L., Zhang, L., Ji, M.B., Li, Q., Yu, M., Shi, G.M., Fan, J., Gong, Z., Wang, X. (2018) Canonical Wnt signaling remodels lipid metabolism in zebrafish hepatocytes following Ras oncogenic insult. Cancer research. 78(19):5548-5560

Eisenhoffer, G.T., Slattum, G., Ruiz, O.E., Otsuna, H., Bryan, C.D., Lopez, J., Wagner, D.S., Bonkowsky, J.L., Chien, C.B., Dorsky, R.I., Rosenblatt, J. (2017) A toolbox to study epidermal cell types in zebrafish. Journal of Cell Science. 130(1):269-277

Kuri, P., Schieber, N.L., Thumberger, T., Wittbrodt, J., Schwab, Y., Leptin, M. (2017) Dynamics of in vivo ASC speck formation. The Journal of cell biology. 216(9):2891-2909

Yang, Q., Yan, C., Gong, Z. (2017) Activation of liver stromal cells is associated with male-biased liver tumor initiation in xmrk and Myc transgenic zebrafish. Scientific Reports. 7:10315

Barber, A.E., Fleming, B.A., Mulvey, M.A. (2016) Similarly Lethal Strains of Extraintestinal Pathogenic Escherichia coli Trigger Markedly Diverse Host Responses in a Zebrafish Model of Sepsis. mSphere. 1(2)

Hatzold, J., Beleggia, F., Herzig, H., Altmüller, J., Nürnberg, P., Bloch, W., Wollnik, B., Hammerschmidt, M. (2016) Tumor suppression in basal keratinocytes via dual non-cell-autonomous functions of a Na,K-ATPase beta subunit. eLIFE. 5:e14277

Mukherjee, K., Ishii, K., Pillalamarri, V., Kammin, T., Atkin, J.F., Hickey, S.E., Xi, Q.J., Gusella, J.F., Talkowski, M.E., Morton, C.C., Maas, R.L., Liao, E.C. (2016) Actin capping protein CAPZB regulates cell morphology, differentiation, and neural crest migration in craniofacial morphogenesis. Human molecular genetics. 25(7):1255-70

Richardson, R., Metzger, M., Knyphausen, P., Ramezani, T., Slanchev, K., Kraus, C., Schmelzer, E., Hammerschmidt, M. (2016) Re-epithelialization of cutaneous wounds in adult zebrafish uses a combination of mechanisms at play during wound closure in embryonic and adult mammals. Development (Cambridge, England). 143(12):2077-88

Zhao, Y., Huang, X., Ding, T.W., Gong, Z. (2016) Enhanced angiogenesis, hypoxia and neutrophil recruitment during Myc-induced liver tumorigenesis in zebrafish. Scientific Reports. 6:31952

Li, Z., Zheng, W., Li, H., Li, C., Gong, Z. (2015) Synergistic Induction of Potential Warburg Effect in Zebrafish Hepatocellular Carcinoma by Co-Transgenic Expression of Myc and xmrk Oncogenes. PLoS One. 10:e0132319

Wang, J., Lee, Y.M., Li, C., Li, P., Li, Z., Lim, T.K., Gong, Z., Lin, Q. (2015) Dramatic improvement of proteomic analysis of zebrafish liver tumor by effective protein extraction with sodium deoxycholate and heat denaturation. International journal of analytical chemistry. 2015:763969

Westcot, S.E., Hatzold, J., Urban, M.D., Richetti, S.K., Skuster, K.J., Harm, R.M., Lopez Cervera, R., Umemoto, N., McNulty, M.S., Clark, K.J., Hammerschmidt, M., Ekker, S.C. (2015) Protein-Trap Insertional Mutagenesis Uncovers New Genes Involved in Zebrafish Skin Development, Including a Neuregulin 2a-Based ErbB Signaling Pathway Required during Median Fin Fold Morphogenesis. PLoS One. 10:e0130688

Fischer, B., Metzger, M., Richardson, R., Knyphausen, P., Ramezani, T., Franzen, R., Schmelzer, E., Bloch, W., Carney, T.J., and Hammerschmidt, M. (2014) p53 and TAp63 promote keratinocyte proliferation and differentiation in breeding tubercles of the zebrafish. PLoS Genetics. 10(1):e1004048

Freisinger, C.M., Huttenlocher, A. (2014) Live Imaging and Gene Expression Analysis in Zebrafish Identifies a Link between Neutrophils and Epithelial to Mesenchymal Transition. PLoS One. 9:e112183

Zheng, W., Li, Z., Nguyen, A.T., Li, C., Emelyanov, A., Gong, Z. (2014) Xmrk, kras and myc transgenic zebrafish liver cancer models share molecular signatures with subsets of human hepatocellular carcinoma. PLoS One. 9:e91179

Asaoka, Y., Terai, S., Sakaida, I., and Nishina, H. (2013) The expanding role of fish models in understanding non-alcoholic fatty liver disease. Disease models & mechanisms. 6(4):905-914

de la Garza, G., Schleiffarth, J.R., Dunnwald, M., Mankad, A., Weirather, J.L., Bonde, G., Butcher, S., Mansour, T.A., Kousa, Y.A., Fukazawa, C.F., Houston, D.W., Manak, J.R., Schutte, B.C., Wagner, D.S., and Cornell, R.A. (2013) Interferon Regulatory Factor 6 Promotes Differentiation of the Periderm by Activating Expression of Grainyhead-Like 3. The Journal of investigative dermatology. 133(1):68-77

Li, Z., Zheng, W., Wang, Z., Zeng, Z., Zhan, H., Li, C., Zhou, L., Yan, C., Spitsbergen, J.M., and Gong, Z. (2013) A transgenic zebrafish liver tumor model with inducible Myc expression reveals conserved Myc signatures with mammalian liver tumors. Disease models & mechanisms. 427(1):223-226

Richardson, R., Slanchev, K., Kraus, C., Knyphausen, P., Eming, S., and Hammerschmidt, M. (2013) Adult zebrafish as a model system for cutaneous wound healing research. The Journal of investigative dermatology. 133(6):1655-65

Eisenhoffer, G.T., Loftus, P.D., Yoshigi, M., Otsuna, H., Chien, C.B., Morcos, P.A., and Rosenblatt, J. (2012) Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia. Nature. 484(7395):546-549

Li, Z., Huang, X., Zhan, H., Zeng, Z., Li, C., Spitsbergen, J.M., Meierjohann, S., Schartl, M., and Gong, Z. (2012) Inducible and repressable oncogene-addicted hepatocellular carcinoma in Tet-on xmrk transgenic zebrafish. Journal of hepatology. 56(2):419-425

Yoo, S.K., Freisinger, C.M., Lebert, D.C., and Huttenlocher, A. (2012) Early redox, Src family kinase, and calcium signaling integrate wound responses and tissue regeneration in zebrafish. The Journal of cell biology. 199(2):225-234

Slanchev, K., Carney, T.J., Stemmler, M.P., Koschorz, B., Amsterdam, A., Schwarz, H., and Hammerschmidt, M. (2009) The epithelial cell adhesion molecule EpCAM is required for epithelial morphogenesis and integrity during zebrafish epiboly and skin development. PLoS Genetics. 5(7):e1000563

Webb, A.E., Sanderford, J., Frank, D., Talbot, W.S., Driever, W., and Kimelman, D. (2007) Laminin alpha5 is essential for the formation of the zebrafish fins. Developmental Biology. 311(2):369-382

Gong, Z., Ju, B., Wang, X., He, J., Wan, H., Mudumana, S.P., and Yan, T. (2002) Green fluorescent protein expression in germ-line transmitted transgenic zebrafish under a stratified epithelial promoter from Keratin8. Developmental Dynamics : an official publication of the American Association of Anatomists. 223(2):204-215

Additional Citations (3):

ZFIN Staff (2015) Data Model Change: Sequence Targeting Reagents Removed from Environment. ZFIN Historical Data.

Zebrafish Nomenclature Committee (2003) Nomenclature Data Curation (2003-2010). Nomenclature Committee Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.