ZFIN ID: ZDB-TALEN-180207-1
TALEN Name: TALEN3-tet2
Target: tet2 (1)
Source:
Target Sequence 1:
5' - CATCCCAGATGGAAT - 3'
   
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Target Sequence 2:
5' - GTTGAAGCAGAAGTT - 3'
   
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  (Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.)
TARGET LOCATIONS
No data available
CONSTRUCTS WITH SEQUENCES FROM TALEN3-tet2 No data available
GENOMIC FEATURES CREATED WITH TALEN3-tet2
Genomic Feature Affected Genomic Regions    
au59 tet2    
GENE EXPRESSION
Gene expression in Wild Types + TALEN3-tet2 No data available
PHENOTYPE
Phenotype resulting from TALEN3-tet2
No data available

Phenotype of all Fish created by or utilizing TALEN3-tet2
Phenotype Fish Conditions Figures
retinal rod cell zpr-3 labeling decreased amount, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 3 with image from Seritrakul et al., 2017
eye decreased size, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 1 with imageFig. 2 with imageFig. 3 with image from Seritrakul et al., 2017
retina cell population proliferation decreased process quality, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 2 with image from Seritrakul et al., 2017
retina nppa expression mislocalised, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 8 with image from Seritrakul et al., 2017
DNA methylation decreased occurrence, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 1 with imageFig. 8 with image from Seritrakul et al., 2017
retina peripheral region wnt9b expression increased distribution, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 6 with image from Seritrakul et al., 2017
cranial nerve II axon decreased amount, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 3 with image from Seritrakul et al., 2017
heart edematous, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 1 with image from Seritrakul et al., 2017
whole organism decreased pigmentation, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 1 with image from Seritrakul et al., 2017
retina peripheral region lacks all parts of type retinal rod cell, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 3 with image from Seritrakul et al., 2017
head decreased size, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 1 with image from Seritrakul et al., 2017
photoreceptor cell opn1sw1 expression decreased amount, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 8 with image from Seritrakul et al., 2017
cranial nerve II absent, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 1 with imageFig. 3 with image from Seritrakul et al., 2017
retina vsx2 expression increased distribution, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 4 with image from Seritrakul et al., 2017
ciliary marginal zone increased size, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 2 with image from Seritrakul et al., 2017
retina central region dla expression increased amount, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 6 with image from Seritrakul et al., 2017
retina peripheral region wnt1 expression increased distribution, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 6 with image from Seritrakul et al., 2017
red sensitive photoreceptor cell photoreceptor outer segment zpr-1 labeling absent, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 3 with image from Seritrakul et al., 2017
cranial nerve II decreased thickness, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 3 with image from Seritrakul et al., 2017
brain nppa expression increased amount, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 8 with image from Seritrakul et al., 2017
head kinked, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 1 with image from Seritrakul et al., 2017
green sensitive photoreceptor cell photoreceptor outer segment zpr-1 labeling absent, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 3 with image from Seritrakul et al., 2017
retina peripheral region lacks all parts of type retinal cone cell, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 3 with image from Seritrakul et al., 2017
Muller cell zrf-1 labeling decreased amount, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 3 with image from Seritrakul et al., 2017
retina central region dla expression mislocalised, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 6 with image from Seritrakul et al., 2017
retinal ganglion cell cell morphogenesis involved in neuron differentiation decreased occurrence, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 3 with image from Seritrakul et al., 2017
brain nppa expression mislocalised, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 8 with image from Seritrakul et al., 2017
retina central region notch1a expression mislocalised, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 6 with image from Seritrakul et al., 2017
retina central region lacks parts or has fewer parts of type retinal cone cell, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 3 with image from Seritrakul et al., 2017
retina peripheral region lef1 expression increased distribution, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 6 with image from Seritrakul et al., 2017
retina central region notch1a expression increased amount, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 6 with image from Seritrakul et al., 2017
retina central region ascl1a expression increased amount, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 6 with image from Seritrakul et al., 2017
photoreceptor cell opn1mw1 expression decreased amount, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 8 with image from Seritrakul et al., 2017
brain increased size, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 1 with image from Seritrakul et al., 2017
retina nppa expression increased amount, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 8 with image from Seritrakul et al., 2017
green sensitive photoreceptor cell zpr-1 labeling decreased amount, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 3 with image from Seritrakul et al., 2017
cranium malformed, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 1 with image from Seritrakul et al., 2017
red sensitive photoreceptor cell zpr-1 labeling decreased amount, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 3 with image from Seritrakul et al., 2017
retina mitotic cell cycle process decreased rate, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 2 with image from Seritrakul et al., 2017
retina central region lacks parts or has fewer parts of type retinal rod cell, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 3 with image from Seritrakul et al., 2017
whole organism Ab1-tet3 labeling absent, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. S3 from Seritrakul et al., 2017
retina cell population proliferation increased process quality, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 2 with image from Seritrakul et al., 2017
whole organism tet2 expression decreased amount, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. S3 from Seritrakul et al., 2017
retina layer formation decreased occurrence, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 1 with image from Seritrakul et al., 2017
retina central region ascl1a expression mislocalised, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 6 with image from Seritrakul et al., 2017
retinal rod cell photoreceptor outer segment zpr-3 labeling absent, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 3 with image from Seritrakul et al., 2017
eye cell decreased amount, abnormal tet2au59/au59 ; tet3au60/au60 standard conditions Fig. 2 with image from Seritrakul et al., 2017
cranial nerve II thickness, ameliorated tet3au60/au60 ; zc7Tg ; tet2au59/au59 chemical treatment by environment: IWR-1-endo Fig. 7 with image from Seritrakul et al., 2017
retinal ganglion cell amount, ameliorated tet3au60/au60 ; zc7Tg ; tet2au59/au59 chemical treatment by environment: IWR-1-endo Fig. 7 with image from Seritrakul et al., 2017
cranial nerve II decreased thickness, abnormal tet3au60/au60 ; zc7Tg ; tet2au59/au59 control Fig. 3 with imageFig. 7 with image from Seritrakul et al., 2017
green sensitive photoreceptor cell GFP expression decreased amount, abnormal tet3au60/au60 ; zc7Tg ; tet2au59/au59 chemical treatment by environment: IWR-1-endo Fig. 7 with image from Seritrakul et al., 2017
retinal ganglion cell amount, ameliorated tet3au60/au60 ; zc7Tg ; tet2au59/au59 chemical treatment by environment: DAPT Fig. 7 with image from Seritrakul et al., 2017
green sensitive photoreceptor cell GFP expression decreased amount, abnormal tet3au60/au60 ; zc7Tg ; tet2au59/au59 chemical treatment by environment: DAPT Fig. 7 with image from Seritrakul et al., 2017
retinal rod cell photoreceptor outer segment zpr-3 labeling absent, abnormal tet3au60/au60 ; zc7Tg ; tet2au59/au59 standard conditions Fig. 3 with image from Seritrakul et al., 2017
retinal ganglion cell decreased amount, abnormal tet3au60/au60 ; zc7Tg ; tet2au59/au59 control Fig. 7 with image from Seritrakul et al., 2017
photoreceptor cell GFP expression decreased amount, abnormal tet3au60/au60 ; zc7Tg ; tet2au59/au59 control Fig. 7 with image from Seritrakul et al., 2017
cranial nerve II axon decreased amount, abnormal tet3au60/au60 ; zc7Tg ; tet2au59/au59 standard conditions Fig. 3 with image from Seritrakul et al., 2017
cranial nerve II absent, abnormal tet3au60/au60 ; zc7Tg ; tet2au59/au59 standard conditions Fig. 3 with image from Seritrakul et al., 2017
cranial nerve II thickness, ameliorated tet3au60/au60 ; zc7Tg ; tet2au59/au59 chemical treatment by environment: DAPT Fig. 7 with image from Seritrakul et al., 2017
Genome Resources:
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