TALEN

TALEN3-tet2

ID

ZDB-TALEN-180207-1

Name

TALEN3-tet2

Previous Names

None

Target

tet2 (1)

Target Sequence 1

5' - CATCCCAGATGGAAT - 3'

Target Sequence 2

5' - GTTGAAGCAGAAGTT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
au59	tet2

Expression

Gene expression in Wild Types + TALEN3-tet2

No data available

Phenotype

Phenotype resulting from TALEN3-tet2

No data available

Phenotype of all Fish created by or utilizing TALEN3-tet2

Phenotype	Fish	Conditions	Figures
retinal rod cell zpr-3 labeling decreased amount, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 3 from Seritrakul et al., 2017
eye decreased size, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 1 , Fig. 2 , Fig. 3 from Seritrakul et al., 2017
retina cell population proliferation decreased process quality, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 2 from Seritrakul et al., 2017
retina nppa expression mislocalised, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 8 from Seritrakul et al., 2017
retina peripheral region wnt9b expression increased distribution, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 6 from Seritrakul et al., 2017
cranial nerve II axon decreased amount, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 3 from Seritrakul et al., 2017
heart edematous, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 1 from Seritrakul et al., 2017
whole organism decreased pigmentation, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 1 from Seritrakul et al., 2017
retina peripheral region lacks all parts of type retinal rod cell, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 3 from Seritrakul et al., 2017
head decreased size, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 1 from Seritrakul et al., 2017
photoreceptor cell opn1sw1 expression decreased amount, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 8 from Seritrakul et al., 2017
cranial nerve II absent, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 1 , Fig. 3 from Seritrakul et al., 2017
retina vsx2 expression increased distribution, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 4 from Seritrakul et al., 2017
ciliary marginal zone increased size, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 2 from Seritrakul et al., 2017
retina central region dla expression increased amount, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 6 from Seritrakul et al., 2017
retina peripheral region wnt1 expression increased distribution, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 6 from Seritrakul et al., 2017
red sensitive photoreceptor cell photoreceptor outer segment zpr-1 labeling absent, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 3 from Seritrakul et al., 2017
cranial nerve II decreased thickness, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 3 from Seritrakul et al., 2017
brain nppa expression increased amount, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 8 from Seritrakul et al., 2017
head kinked, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 1 from Seritrakul et al., 2017
green sensitive photoreceptor cell photoreceptor outer segment zpr-1 labeling absent, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 3 from Seritrakul et al., 2017
retina peripheral region lacks all parts of type retinal cone cell, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 3 from Seritrakul et al., 2017
Muller cell zrf-1 labeling decreased amount, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 3 from Seritrakul et al., 2017
retina central region dla expression mislocalised, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 6 from Seritrakul et al., 2017
retinal ganglion cell cell morphogenesis involved in neuron differentiation decreased occurrence, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 3 from Seritrakul et al., 2017
brain nppa expression mislocalised, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 8 from Seritrakul et al., 2017
retina central region notch1a expression mislocalised, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 6 from Seritrakul et al., 2017
retina central region lacks parts or has fewer parts of type retinal cone cell, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 3 from Seritrakul et al., 2017
retina peripheral region lef1 expression increased distribution, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 6 from Seritrakul et al., 2017
retina central region notch1a expression increased amount, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 6 from Seritrakul et al., 2017
retina central region ascl1a expression increased amount, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 6 from Seritrakul et al., 2017
whole organism 5-(hydroxymethyl)cytosine decreased amount, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 1 , Fig. 8 from Seritrakul et al., 2017
photoreceptor cell opn1mw1 expression decreased amount, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 8 from Seritrakul et al., 2017
brain increased size, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 1 from Seritrakul et al., 2017
retina nppa expression increased amount, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 8 from Seritrakul et al., 2017
green sensitive photoreceptor cell zpr-1 labeling decreased amount, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 3 from Seritrakul et al., 2017
cranium malformed, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 1 from Seritrakul et al., 2017
red sensitive photoreceptor cell zpr-1 labeling decreased amount, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 3 from Seritrakul et al., 2017
retina mitotic cell cycle process decreased rate, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 2 from Seritrakul et al., 2017
retina central region lacks parts or has fewer parts of type retinal rod cell, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 3 from Seritrakul et al., 2017
whole organism Ab1-tet3 labeling absent, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. S3 from Seritrakul et al., 2017
retina cell population proliferation increased process quality, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 2 from Seritrakul et al., 2017
whole organism tet2 expression decreased amount, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. S3 from Seritrakul et al., 2017
retina layer formation decreased occurrence, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 1 from Seritrakul et al., 2017
retina central region ascl1a expression mislocalised, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 6 from Seritrakul et al., 2017
retinal rod cell photoreceptor outer segment zpr-3 labeling absent, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 3 from Seritrakul et al., 2017
eye cell decreased amount, abnormal	tet2^au59/au59; tet3^au60/au60	standard conditions	Fig. 2 from Seritrakul et al., 2017
cranial nerve II thickness, ameliorated	tet2^au59/au59; tet3^au60/au60; zc7Tg	chemical treatment by environment: IWR-1-endo	Fig. 7 from Seritrakul et al., 2017
retinal ganglion cell amount, ameliorated	tet2^au59/au59; tet3^au60/au60; zc7Tg	chemical treatment by environment: IWR-1-endo	Fig. 7 from Seritrakul et al., 2017
cranial nerve II decreased thickness, abnormal	tet2^au59/au59; tet3^au60/au60; zc7Tg	standard conditions	Fig. 3 , Fig. 7 from Seritrakul et al., 2017
green sensitive photoreceptor cell GFP expression decreased amount, abnormal	tet2^au59/au59; tet3^au60/au60; zc7Tg	chemical treatment by environment: IWR-1-endo	Fig. 7 from Seritrakul et al., 2017
retinal ganglion cell amount, ameliorated	tet2^au59/au59; tet3^au60/au60; zc7Tg	chemical treatment by environment: DAPT	Fig. 7 from Seritrakul et al., 2017
green sensitive photoreceptor cell GFP expression decreased amount, abnormal	tet2^au59/au59; tet3^au60/au60; zc7Tg	chemical treatment by environment: DAPT	Fig. 7 from Seritrakul et al., 2017
retinal rod cell photoreceptor outer segment zpr-3 labeling absent, abnormal	tet2^au59/au59; tet3^au60/au60; zc7Tg	standard conditions	Fig. 3 from Seritrakul et al., 2017
retinal ganglion cell decreased amount, abnormal	tet2^au59/au59; tet3^au60/au60; zc7Tg	control	Fig. 7 from Seritrakul et al., 2017
photoreceptor cell GFP expression decreased amount, abnormal	tet2^au59/au59; tet3^au60/au60; zc7Tg	control	Fig. 7 from Seritrakul et al., 2017
cranial nerve II axon decreased amount, abnormal	tet2^au59/au59; tet3^au60/au60; zc7Tg	standard conditions	Fig. 3 from Seritrakul et al., 2017
cranial nerve II absent, abnormal	tet2^au59/au59; tet3^au60/au60; zc7Tg	standard conditions	Fig. 3 from Seritrakul et al., 2017
cranial nerve II thickness, ameliorated	tet2^au59/au59; tet3^au60/au60; zc7Tg	chemical treatment by environment: DAPT	Fig. 7 from Seritrakul et al., 2017

Citations