ZFIN ID: ZDB-GENE-090312-98
Gene Name: tet methylcytosine dioxygenase 2
Gene Symbol: tet2
Sequence Ontology ID : SO:0000704

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Previous Names: im:7136741, si:ch211-216c6.1

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(Including Attributions)
Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 7 figures from 6 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7136741]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  brain, dorsal aorta, gill, head (all 21) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb2019 Insertion Unknown Unknown TALEN
mk17 Small Deletion Exon 8 Frameshift, Premature Stop TALEN
sa8671 Point Mutation Unknown Premature Stop ENU
sa11184 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13278 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa14623 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32686 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • zdf20 Small Deletion Exon 7 Premature Stop ZINC_FINGER_NUCLEASE
    zdf21 Small Deletion Exon 7 Premature Stop ZINC_FINGER_NUCLEASE
    Targeting reagents: MO1-tet2 (1), MO2-tet2 (1), TALEN1-tet2 (1), TALEN2-tet2 (1)
    PHENOTYPE
    Data: 8 figures from 2 publications
    Observed in: blood nucleate erythrocyte, erythrocyte differentiation, erythroid progenitor cell, head kidney common myeloid progenitor (all 17) expand
    DISEASE ASSOCIATED WITH tet2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    myelodysplastic syndrome Myelodysplastic syndrome, somatic 614286
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process endothelial to hematopoietic transition (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR024779 (1)
  • Pfam:PF12851 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tet2-001 (1) 8807
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tet2 No data available
    MARKER RELATIONSHIPS
    tet2Contained in: [BAC] CH211-216C6 (1) (order this)
    tet2Encodes: [EST] IMAGE:7136741 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005159903 (1)
    Genomic GenBank:CU570873 (1) 197580bp
    Select Tool
    Polypeptide UniProtKB:E7F958 (1) 1715aa
    Sequence Information (all 10)
    OTHER tet2 GENE PAGES
  • Alliance (1)
  • Gene:101887161 (1)
  • VEGA:OTTDARG00000030173 (1)
  • Ensembl(GRCz10):ENSDARG00000076928 (1)
  • ORTHOLOGY for tet2 (Chr: 1)
    CITATIONS (26)