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ZIRC
ZFIN ID: ZDB-GENE-090312-98
Gene Name: tet methylcytosine dioxygenase 2
Gene Symbol: tet2
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: im:7136741, si:ch211-216c6.1

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(Including Attributions)
Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits methylcytosine dioxygenase activity. Involved in several processes, including cell surface receptor signaling pathway; endothelial to hematopoietic transition; and primitive erythrocyte  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
au59 Small Deletion Exon 1 Frameshift, Premature Stop TALEN
ihb2019 Insertion Exon 2 Unknown TALEN
mk17 Small Deletion Exon 8 Frameshift, Premature Stop TALEN
sa8671 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11184 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13278 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14623 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32686 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zdf20 Small Deletion Exon 7 Premature Stop ZINC_FINGER_NUCLEASE
    zdf21 Small Deletion Exon 7 Premature Stop ZINC_FINGER_NUCLEASE
    Targeting reagents:
    DISEASE ASSOCIATED WITH tet2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    myelodysplastic syndrome Myelodysplastic syndrome, somatic 614286
    DISEASE ASSOCIATED WITH tet2 VIA EXPERIMENTAL MODELS
    Human Disease Fish Conditions Citations
    myelodysplastic syndrome tet2zdf20/zdf20 standard conditions Gjini et al., 2015
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell morphogenesis involved in differentiation (more)
    Cellular Component nucleus (more)
    Molecular Function methylcytosine dioxygenase activity (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR024779 (1)
  • InterPro:IPR040175 (1)
  • Pfam:PF12851 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tet2-201 (1) 8807
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tet2 No data available
    MARKER RELATIONSHIPS
    tet2Contained in: [BAC] CH211-216C6 (1) (order this)
    tet2Encodes: [EST] IMAGE:7136741 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005159903 (1)
    Genomic GenBank:CU570873 (1) 197580bp
    Select Tool
    Polypeptide UniProtKB:E7F958 (1) 1715aa
    Sequence Information (all 12)
    ORTHOLOGY for tet2 (Chr: 1)
    CITATIONS (35)