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Fig. 3 ngn1 is expressed earlier and more widely than zebrafish nrd and isl-1. (A,B) nrd expression in 1-somite stage embryos. nrd is expressed in a row of cells in the anterior neural plate (arrowhead in A), the trigeminal ganglion (tg) and in two lateral rows of cells in the trunk neural plate (arrow in B). Dorsal views onto anterior neural plate (A) and at mid trunk level (B). (C,D) isl-1 expression in 1s embryos. isl-1 is expressed in the pillow (arrow head in C); the trigeminal ganglion (tg) and in two medial and two lateral rows of cells in the posterior neural plate (arrows in D). Dorsal views onto anterior neural plate (C) and at mid trunk level (D). (E) ngn1 expression in 1-somite stage embryo. Dorsal view onto neural plate at posterior hindbrain/anterior trunk level. (F) ngn1 expression at the 90% epiboly stage; view is dorsal onto the hindbrain anlage, anterior up. ngn1 is already expressed whereas isl-1 and nrd are not expressed in the late gastrula. The lateral extent of the neural plate is marked by arrowheads; arrows indicate the trigeminal ganglia, which are widely spaced at this stage. Abbreviations: tg, trigeminal ganglion.