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General Information
ZIRC
ZFIN ID: ZDB-GENE-980526-112
Gene Name: ISL LIM homeobox 1
Gene Symbol: isl1
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: Isl-1 (1), islet-1

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including atrial cardiac muscle cell differentiation; neuron differentiation;  ...
GENE EXPRESSION
All Expression Data: 274 figures from 195 publications
Directly Submitted Expression Data: 6 figures (12 images) from Thisse et al., 2004 [MGC:73031]
  6 figures (12 images) from Thisse et al., 2005 [eu243]
Wild-type Stages, Structures: Gastrula:Bud (10.0h-10.33h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
rw436 Point Mutation Unknown Cryptic Acceptor Splice Site, Frameshift, Premature Stop ENU
sa29 Point Mutation Unknown Premature Stop ENU
Targeting reagents:
DISEASE ASSOCIATED WITH isl1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH isl1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process exocrine pancreas development (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 26)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA isl1-201 (1) 2303
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIES
PLASMIDSNo data available
MARKER RELATIONSHIPS
isl1Contained in: [BAC] CH211-219F7 (1) (order this)
isl1Contains: [SNP] rs3727897 (1)
isl1Encodes: [EST] eu243 (1)
[cDNA] MGC:73031 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_130962 (1) 2275bp
Genomic GenBank:AL954694 (1) 111431bp
Select Tool
Polypeptide UniProtKB:P53405 (1) 349aa
Sequence Clusters UniGene:75106 (1)
Sequence Information (all 21)
ORTHOLOGY for isl1 (Chr: 5)
CITATIONS (387)