ZFIN ID: ZDB-GENE-980526-112
Gene Name: ISL LIM homeobox 1
Gene Symbol: isl1
Sequence Ontology ID : SO:0000704

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Previous Names: Isl-1 (1), islet-1

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 263 figures from 188 publications
Directly Submitted Expression Data: 6 figures (12 images) from Thisse et al., 2004 [MGC:73031]
  6 figures (12 images) from Thisse et al., 2005 [eu243]
Wild-type Stages, Structures: Gastrula:Bud (10.0h-10.33h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
rw436 Point Mutation Unknown Cryptic Acceptor Splice Site, Frameshift, Premature Stop ENU
sa29 Point Mutation Unknown Unknown ENU
Targeting reagents:
PHENOTYPE
Data: 26 figures from 10 publications
Observed in:
DISEASE ASSOCIATED WITH isl1 HUMAN ORTHOLOG No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process exocrine pancreas development (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 25)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR001781 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS00478 (1)
  • PROSITE:PS50023 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF00412 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA isl1-001 (1) 2303
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM isl1
    MARKER RELATIONSHIPS
    isl1Contained in: [BAC] CH211-219F7 (1) (order this)
    isl1Contains: [SNP] rs3727897 (1)
    isl1Encodes: [EST] eu243 (1)
    [cDNA] MGC:73031 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_130962 (1) 2275bp
    Genomic GenBank:AL954694 (1) 111431bp
    Select Tool
    Polypeptide UniProtKB:P53405 (1) 349aa
    Sequence Clusters UniGene:75106 (1)
    Sequence Information (all 21)
    OTHER isl1 GENE PAGES
  • Alliance (1)
  • Gene:30147 (1)
  • VEGA:OTTDARG00000018571 (1)
  • Ensembl(GRCz11):ENSDARG00000004023 (1)
  • ORTHOLOGY for isl1 (Chr: 5)
    CITATIONS (372)