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Fig. 1 Expression of genes encoding components of the zebrafish Nod signaling pathway. (A) Detection of gene expression, by whole-mount in situ hybridization, in 4 dpf (nod1, ripk2, a20, erbin and grim-19) and 5 dpf (nod2, aamp, cd147 and centaurin b1) zebrafish larvae. All specimens are oriented anterior to the left, posterior to the right. Red arrows indicate the gut. Green arrow indicates liver. (B,C) Differential expression of Nod signaling pathway components in myelomonocytic cells from zebrafish larvae (B) and adults (C). Error bars represent s.e.m.; statistically significant differences of P<0.05 (*) and P<0.01 (**) are marked.

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