Gene
ripk2
- ID
- ZDB-GENE-030902-3
- Name
- receptor-interacting serine-threonine kinase 2
- Symbol
- ripk2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have CARD domain binding activity and JUN kinase kinase kinase activity. Involved in defense response to other organism and regulation of transcription, DNA-templated. Predicted to localize to cytoplasm. Is expressed in brain; gill; liver; pleuroperitoneal region; and unfertilized egg. Orthologous to human RIPK2 (receptor interacting serine/threonine kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001315 | CARD domain |
| Domain | IPR042149 | RIP2, CARD domain |
| Family | IPR017322 | Receptor-interacting serine/threonine-protein kinase 2 |
| Family | IPR050167 | Serine/threonine-protein kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR011029 | Death-like domain superfamily |
Domain Details Per Protein
| Protein | Length | CARD domain | Death-like domain superfamily | Protein kinase domain | Protein kinase-like domain superfamily | Receptor-interacting serine/threonine-protein kinase 2 | RIP2, CARD domain | Serine/threonine-protein kinase | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q4V958
|
584 |
Interactions and Pathways
No data available
Plasmids
No data available