ZFIN ID: ZDB-GENE-061103-403
Gene Name: erbb2 interacting protein
Gene Symbol: erbin    Nomenclature History

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Previous Names: erbb2ip (1), zgc:152984 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have ErbB-2 class receptor binding activity. Predicted to be involved in several processes, including establishment or maintenance of epithelial cell apical/basal polarity; neurotransmitter receptor transport; and receptor clustering. Predicted to colocalize with ionotropic glutamate receptor complex and postsynaptic membrane. Is expressed in intestine. Orthologous to human ERBIN (erbb2 interacting protein).
Genome Resources: Alliance (1),  Gene:566811 (1),  Ensembl(GRCz11):ENSDARG00000044281 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Larval:Day 4 (96.0h-120.0h) to Larval:Day 4 (96.0h-120.0h)
 
PHENOTYPE No data available
DISEASE ASSOCIATED WITH erbin HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH erbin VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process negative regulation of NF-kappaB transcription factor activity (more)
Cellular Component basolateral plasma membrane (more)
Molecular Function ErbB-2 class receptor binding (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA erbin-201 (1)    Ensembl 4165
erbin-203 (1)    Ensembl 4916
ncRNA erbb2ip-003 (1)    Ensembl 679
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM erbin No data available
MARKER RELATIONSHIPS
erbin Contained in: [BAC] CH211-117O11 (1), CH211-276M8 (1), DKEYP-1D6 (1)
erbin Encodes: [EST] wz11037
[cDNA] MGC:152984 (1), MGC:198347 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001193543 (1) 7498 nt
Genomic GenBank:CR925725 (1) 171074 nt
Select Tool
Polypeptide UniProtKB:E7EYJ7 (1) 1382 aa
Sequence Information (all 33)
ORTHOLOGY for erbin ( Chr: 10 )
CITATIONS (22)