Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-990914-3
Gene Name: glial fibrillary acidic protein
Gene Symbol: gfap
Previous Names: af506734 (1), cb345 (1), etID36982.3 (1), wu:fb34h11 (1), wu:fk42c12, xx:af506734 (1), zgc:110485, zrf-1 antigen (1)
Nomenclature History
GENE EXPRESSION
All Expression Data: 60 figures from 38 publications
Directly Submitted Expression Data: 6 figures (12 images) from Thisse et al., 2001 [cb345]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Adult (90d-730d, breeding adult)
  alar plate midbrain region, astrocyte, basal plate midbrain region, brain (all 38) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa20045
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Alexander disease 203450
GENE ONTOLOGY
Ontology GO Term
Cellular Component cytoplasm (more)
Molecular Function structural molecule activity (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001664 (1)
  • InterPro:IPR002957 (1)
  • InterPro:IPR006821 (1)
  • InterPro:IPR018039 (1)
  • PROSITE:PS00226 (1)
  • Pfam:PF00038 (1)
  • Pfam:PF04732 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA gfap-001 (1) 2651
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    Ab1-gfap (1), Ab2-gfap (1), Ab4-gfap (1), zrf-1 (1)
    CONSTRUCTS WITH SEQUENCES FROM gfap
    Tg(2.3gfap:GFP), Tg(gfap:EGFP), Tg(gfap:GFP), Tg(gfap:LEXPR,LEXOP:EGFP), Tg(gfap:nGFP) (all 7) expand
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    gfap Contained in: [BAC] DKEY-15N1 (1)
    gfap Contains: [SNP] rs3727711 (1)
    gfap Encodes: [EST] af506734, cb345 (1) (order this), fb34h11 (1), fk42c12 (1)
    [cDNA] MGC:110485 (1) (order this), MGC:191386 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131373 (1) 2570 bp
    Genomic GenBank:BX324157 (1) 272769 bp Blast at MegaBLAST
    Polypeptide UniProtKB:B2GP50 (1) 444 aa
    Sequence Clusters UniGene:32667 (1)
    Sequence Information (all 46)
    OTHER gfap GENE PAGES
  • Gene:30646 (1)
  • VEGA:OTTDARG00000019974 (1)
  • Ensembl(Zv9):ENSDARG00000025301 (1)
  • MAPPING INFORMATION
    Chr: 3 Details View Map: Merged   Individual Panels
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA NT CL
    Zebrafish gfap 3  
    Human GFAP 17 (17q21)
  • OMIM:137780
  • Gene:2670
  • Mouse Gfap 11 ( 66.48 cM)
  • MGI:95697
  • Gene:14580
  • CITATIONS (90)