Gene
tenm4
- ID
- ZDB-GENE-990714-20
- Name
- teneurin transmembrane protein 4
- Symbol
- tenm4 Nomenclature History
- Previous Names
-
- tenm4
- nrg1
- odz4
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have cell adhesion molecule binding activity; protein heterodimerization activity; and protein homodimerization activity. Involved in axon guidance. Predicted to localize to several cellular components, including neuron projection; nucleus; and plasma membrane. Is expressed in several structures, including brain; midbrain hindbrain boundary neural rod; neural tube; optic vesicle; and retina. Human ortholog(s) of this gene implicated in essential tremor 5. Orthologous to human TENM4 (teneurin transmembrane protein 4).
- Genome Resources
- Note
- None
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- No data available
- Thisse Expression Data
-
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Hor et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
essential tremor 5 | Alliance | Essential tremor, hereditary, 5 | 616736 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000742 | EGF-like domain |
Domain | IPR009471 | Teneurin intracellular, N-terminal |
Domain | IPR022385 | Rhs repeat-associated core |
Domain | IPR028916 | Tox-GHH domain |
Family | IPR027691 | Teneurin-3/4 |
Homologous_superfamily | IPR008969 | Carboxypeptidase-like, regulatory domain superfamily |
Homologous_superfamily | IPR011041 | Soluble quinoprotein glucose/sorbosone dehydrogenase |
Homologous_superfamily | IPR011042 | Six-bladed beta-propeller, TolB-like |
Repeat | IPR006530 | YD repeat |
Repeat | IPR031325 | RHS repeat |
Domain Details Per Protein
Protein | Length | Carboxypeptidase-like, regulatory domain superfamily | EGF-like domain | RHS repeat | Rhs repeat-associated core | Six-bladed beta-propeller, TolB-like | Soluble quinoprotein glucose/sorbosone dehydrogenase | Teneurin-3/4 | Teneurin intracellular, N-terminal | Tox-GHH domain | YD repeat |
---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A286Y9C5
|
2865 | ||||||||||
UniProtKB:A0A2R8QIZ5
|
2840 | ||||||||||
UniProtKB:A0A0R4ICV6
|
2831 | ||||||||||
UniProtKB:A0A2R8Q661
|
2792 | ||||||||||
UniProtKB:A0A0R4IN22
|
2824 | ||||||||||
UniProtKB:A0A0R4IGJ8
|
2772 | ||||||||||
UniProtKB:Q9W7R3
|
2824 | ||||||||||
UniProtKB:A0A0R4IZR2
|
83 | ||||||||||
UniProtKB:A0A2R8RZ80
|
2798 |
Interactions and Pathways
No data available
Plasmids
No data available
- Gene Tree
- Ensembl