Gene

tenm4

ID
ZDB-GENE-990714-20
Name
teneurin transmembrane protein 4
Symbol
tenm4 Nomenclature History
Previous Names
  • tenm4
  • nrg1
  • odz4
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to have cell adhesion molecule binding activity; protein heterodimerization activity; and protein homodimerization activity. Involved in axon guidance. Predicted to localize to several cellular components, including neuron projection; nucleus; and plasma membrane. Is expressed in several structures, including brain; midbrain hindbrain boundary neural rod; neural tube; optic vesicle; and retina. Human ortholog(s) of this gene implicated in essential tremor 5. Orthologous to human TENM4 (teneurin transmembrane protein 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Hor et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tenm4 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
essential tremor 5 Alliance Essential tremor, hereditary, 5 616736
Associated With tenm4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000742 EGF-like domain
Domain IPR009471 Teneurin intracellular, N-terminal
Domain IPR022385 Rhs repeat-associated core
Domain IPR028916 Tox-GHH domain
Family IPR027691 Teneurin-3/4
Homologous_superfamily IPR008969 Carboxypeptidase-like, regulatory domain superfamily
Homologous_superfamily IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase
Homologous_superfamily IPR011042 Six-bladed beta-propeller, TolB-like
Repeat IPR006530 YD repeat
Repeat IPR031325 RHS repeat
Domain Details Per Protein
Protein Length Carboxypeptidase-like, regulatory domain superfamily EGF-like domain RHS repeat Rhs repeat-associated core Six-bladed beta-propeller, TolB-like Soluble quinoprotein glucose/sorbosone dehydrogenase Teneurin-3/4 Teneurin intracellular, N-terminal Tox-GHH domain YD repeat
UniProtKB:A0A286Y9C5 2865
UniProtKB:A0A0R4IN22 2824
UniProtKB:A0A0R4IGJ8 2772
UniProtKB:A0A2R8RZ80 2798
UniProtKB:A0A2R8Q661 2792
UniProtKB:Q9W7R3 2824
UniProtKB:A0A0R4IZR2 83
UniProtKB:A0A0R4ICV6 2831
UniProtKB:A0A2R8QIZ5 2840
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations