Gene

tenm4

ID
ZDB-GENE-990714-20
Name
teneurin transmembrane protein 4
Symbol
tenm4 Nomenclature History
Previous Names
  • tenm4
  • nrg1
  • odz4
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to have cell adhesion molecule binding activity; protein heterodimerization activity; and protein homodimerization activity. Involved in axon guidance. Predicted to localize to several cellular components, including neuron projection; nucleus; and plasma membrane. Is expressed in several structures, including brain; midbrain hindbrain boundary neural rod; neural tube; optic vesicle; and retina. Human ortholog(s) of this gene implicated in essential tremor 5. Orthologous to human TENM4 (teneurin transmembrane protein 4).
Genome Resources
Note
None
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Hor et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tenm4 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
essential tremor 5 Alliance Essential tremor, hereditary, 5 616736
Associated With tenm4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000742 EGF-like domain
Domain IPR009471 Teneurin intracellular, N-terminal
Domain IPR022385 Rhs repeat-associated core
Domain IPR028916 Tox-GHH domain
Family IPR027691 Teneurin-3/4
Homologous_superfamily IPR008969 Carboxypeptidase-like, regulatory domain superfamily
Homologous_superfamily IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase
Homologous_superfamily IPR011042 Six-bladed beta-propeller, TolB-like
Repeat IPR006530 YD repeat
Repeat IPR031325 RHS repeat
Domain Details Per Protein
Protein Length Carboxypeptidase-like, regulatory domain superfamily EGF-like domain RHS repeat Rhs repeat-associated core Six-bladed beta-propeller, TolB-like Soluble quinoprotein glucose/sorbosone dehydrogenase Teneurin-3/4 Teneurin intracellular, N-terminal Tox-GHH domain YD repeat
UniProtKB:A0A286Y9C5 2865
UniProtKB:A0A2R8QIZ5 2840
UniProtKB:A0A0R4ICV6 2831
UniProtKB:A0A2R8Q661 2792
UniProtKB:A0A0R4IN22 2824
UniProtKB:A0A0R4IGJ8 2772
UniProtKB:Q9W7R3 2824
UniProtKB:A0A0R4IZR2 83
UniProtKB:A0A2R8RZ80 2798
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations