ZFIN Gene: tbx16

ZFIN ID: ZDB-GENE-990615-5

ZFIN ID: ZDB-GENE-990615-5

Gene Name:

T-box transcription factor 16

Gene Symbol:

tbx16

Sequence Ontology ID :

SO:0000704

Previous Names:

cb103 (1), id:ibd2185 (1), spadetail, spt-1 (1), spt (1), wu:fa17g07 (1), ZF-SPT (1), zgc:109817

Location:

Chr: 8 Mapping Details/Browsers

Nomenclature History

AUTOMATED DESCRIPTION

Exhibits transcription regulatory region DNA binding activity. Involved in several processes, including animal organ development; blood vessel morphogenesis; and regulation of embryonic development. ...

GENE EXPRESSION
All Expression Data:	87 figures from 60 publications
Directly Submitted Expression Data:	6 figures (10 images) from Thisse et al., 2001 [cb103]
	4 figures (10 images) from Kudoh et al., 2001 [ibd2185]
Wild-type Stages, Structures:	Cleavage:64-cell (2.0h-2.25h) to Pharyngula:Prim-25 (36.0h-42.0h)
	adaxial cell nucleus adaxial cell anterior axial hypoblast DoLA epiblast forerunner cell group germ ring lateral region germ ring nucleus germ ring ventral region germ ring hypoblast margin ventro-lateral region margin mesoderm neural tube neuron paraxial mesoderm polster prechordal plate presumptive mesoderm presumptive paraxial mesoderm presumptive segmental plate segmental plate nucleus segmental plate somite spinal cord neuron spinal cord tail bud epiblast tail bud nucleus tail bud unspecified whole organism
Curated Microarray Expression:	GEO (1)

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
b104	Indel	Unknown	Premature Stop	SPONTANEOUS	Zebrafish International Resource Center (ZIRC) (order this)
hi2109Tg	Transgenic Insertion	Intron 1	Unknown	DNA
hi3714Tg	Transgenic Insertion	Intron 1	Unknown	DNA	Zebrafish International Resource Center (ZIRC) (order this)
kt378b	Point Mutation	Acceptor Splice Site of Intron 1	Unknown	ENU
la016429Tg	Transgenic Insertion	Unknown	Unknown	DNA	Zebrafish International Resource Center (ZIRC) (order this)
la026643Tg	Transgenic Insertion	Unknown	Unknown	DNA	Zebrafish International Resource Center (ZIRC) (order this)
la026644Tg	Transgenic Insertion	Unknown	Unknown	DNA	Zebrafish International Resource Center (ZIRC) (order this)
la029508Tg	Transgenic Insertion	Unknown	Unknown	DNA
m423	Point Mutation	Unknown	Unknown	ENU	Zebrafish International Resource Center (ZIRC) (order this)
tbx16_unspecified	Unspecified	Unknown	Unknown
thp003	Point Mutation	Unknown	Missense	ENU
tm41	Unknown	Unknown	Unknown	ENU	European Zebrafish Resource Center (EZRC) (order this)
tq5	Unknown	Unknown	Unknown	ENU	European Zebrafish Resource Center (EZRC) (order this)

Targeting reagents:

PHENOTYPE

Data:

59 figures from 32 publications

Observed in:

DISEASE ASSOCIATED WITH tbx16 HUMAN ORTHOLOG No data available

DISEASE ASSOCIATED WITH tbx16 VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	digestive tract development (more)
Cellular Component	nuclear chromatin (more)
Molecular Function	DNA binding (more)

GO Terms (all 40)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR001699 (1) InterPro:IPR008967 (1) InterPro:IPR018186 (1) InterPro:IPR036960 (1)	PROSITE:PS01264 (1) PROSITE:PS01283 (1) PROSITE:PS50252 (1)	Pfam:PF00907 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	tbx16-201 (1)	4949	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

GENE PRODUCT DESCRIPTION

INTERACTIONS AND PATHWAYS

ANTIBODIES

Ab2-tbx16 (1)
AB3-tbx16 (1)

PLASMIDSNo data available

CONSTRUCTS WITH SEQUENCES FROM tbx16

MARKER RELATIONSHIPS

tbx16Contained in:	[BAC] CH73-313L22 (1) (order this)
tbx16Encodes:	[EST] cb103 (1) (order this), fa17g07 (1), ibd2185 (order this) [STS] chunp30288 [cDNA] MGC:109817 (1) (order this), MGC:193075 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_131058 (1)	2561bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CU459194 (1)	101559bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:B8JL25 (1)	470aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast
Sequence Clusters	UniGene:75456 (1)

Sequence Information (all 24)

OTHER tbx16 GENE PAGES

Alliance (1)

Gene:30264 (1)

VEGA:OTTDARG00000028936 (1)

Ensembl(GRCz11):ENSDARG00000007329 (1)

ORTHOLOGY for tbx16 (Chr: 8)

CITATIONS (252)

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