Gene

tbx16

ID

ZDB-GENE-990615-5

Name

T-box transcription factor 16

Symbol

tbx16 Nomenclature History

Previous Names

cb103 (1)
id:ibd2185 (1)
spadetail
spt-1 (1)
spt (1)
wu:fa17g07 (1)
ZF-SPT (1)
zgc:109817

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Exhibits transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; blood vessel morphogenesis; and regulation of embryonic development. Localizes to nuclear chromatin. Is expressed in several structures, including forerunner cell group; germ ring; mesoderm; presumptive mesoderm; and spinal cord.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

90 figures from 63 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

cb103 (10 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 60 figures from 33 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tbx16 Human Ortholog

No data available

Associated With tbx16 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018186	Transcription factor, T-box, conserved site
Homologous_superfamily	IPR008967	p53-like transcription factor, DNA-binding
Homologous_superfamily	IPR036960	T-box superfamily