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ZIRC
ZFIN ID: ZDB-GENE-990415-94
Gene Name: heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1
Gene Symbol: hsp90aa1.1    Nomenclature History

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Previous Names: akineto, fb17b01, hsp90, hsp90a.1, hsp90a (1), hsp90alpha, slo, sloth, wu:fb17b01 (1), zgc:86652 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have several functions, including ATP binding activity; disordered domain specific binding activity; and unfolded protein binding activity. Involved in leukocyte migration; myofibril assembly; and response to metal ion. Localizes to the Z disc. Is expressed in several structures, including immature eye; musculature system; paraxial mesoderm; pericardial region; and skeletal muscle myoblast. Orthologous to human HSP90AA1 (heat shock protein 90 alpha family class A member 1).
Genome Resources: Alliance (1),  Gene:30591 (1),  Ensembl(GRCz11):ENSDARG00000010478 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la028290Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1396 Point Mutation Unknown Premature Stop ENU
    sa14009 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16631 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa30722 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tm201 Point Mutation Exon 10 Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tu44c Point Mutation Exon 9 Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • u45 Point Mutation Exon 3 Missense ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-hsp90aa1.1
    1
    CRISPR2-hsp90aa1.1
    1
    CRISPR3-hsp90aa1.1
    1
    CRISPR4-hsp90aa1.1
    1
    MO1-hsp90aa1.1 N/A 2
    MO1-hsp90aa1.1,hsp90aa1.2 N/A 1
    MO2-hsp90aa1.1 N/A 3
    MO3-hsp90aa1.1 N/A 2
    MO4-hsp90aa1.1 N/A 5
    MO5-hsp90aa1.1 N/A 1
    DISEASE ASSOCIATED WITH hsp90aa1.1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hsp90aa1.1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to metal ion (more)
    Cellular Component Z disc (more)
    Molecular Function protein binding (more)
    GO Terms (all 32)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hsp90aa1.1-201 (1)    Ensembl 2543
    ncRNA hsp90aa1.1-002 (1) 283
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hsp90aa1.1 No data available
    MARKER RELATIONSHIPS
    hsp90aa1.1 Contained in: [BAC] DKEY-241L7 (1) (order this)
    hsp90aa1.1 Encodes: [EST] fb17b01 (1) (order this)
    [cDNA] MGC:86652 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131328 (1) 2482 bp
    Genomic GenBank:CR381646 (1) 183151 bp
    Select Tool
    Polypeptide UniProtKB:Q90474 (1) 725 aa
    Sequence Clusters UniGene:75834 (1)
    Sequence Information (all 17)
    ORTHOLOGY for hsp90aa1.1 ( Chr: 20 )
    CITATIONS (104)