ZFIN ID: ZDB-GENE-990415-165
Gene Name: myostatin b
Gene Symbol: mstnb
Sequence Ontology ID : SO:0000704

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Previous Names: mstn-1 (1), mstn, gdf8 (1), zgc:109749

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits growth factor activity; involved in several processes, including immune response, negative regulation of growth rate, and negative regulation of skeletal muscle tissue development; predicted  ...
GENE EXPRESSION
All Expression Data: 19 figures from 15 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:109749]
  1 figure (1 image) from Thisse et al., 2005 [eu171]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
bns5 Small Deletion Unknown Unknown TALEN
cig3 Small Deletion Unknown Premature Stop CRISPR
ihb167 Indel Unknown Unknown TALEN
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
  • sa41499 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zf1027 Indel Exon 1 Premature Stop TALEN
    Targeting reagents:
    PHENOTYPE
    Data: 7 figures from 3 publications
    Observed in:
    DISEASE ASSOCIATED WITH mstnb HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    myostatin-related muscle hypertrophy Muscle hypertrophy 614160
    DISEASE ASSOCIATED WITH mstnb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process muscle organ development (more)
    Cellular Component extracellular region (more)
    Molecular Function growth factor activity (more)
    GO Terms (all 22)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001111 (1)
  • InterPro:IPR001839 (1)
  • InterPro:IPR015615 (1)
  • InterPro:IPR017948 (1)
  • InterPro:IPR029034 (1)
  • PROSITE:PS00250 (1)
  • PROSITE:PS51362 (1)
  • Pfam:PF00019 (1)
  • Pfam:PF00688 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA mstnb-201 (1) 2178
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM mstnb
    MARKER RELATIONSHIPS
    mstnbContained in: [BAC] CH211-3O3 (1) (order this)
    [PAC] BUSM1-72B14 (1) (order this)
    mstnbEncodes: [EST] eu171 (1)
    [cDNA] MGC:109749 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131019 (1) 2179bp
    Genomic GenBank:BX323586 (1) 171172bp
    Select Tool
    Polypeptide UniProtKB:O42222 (1) 374aa
    Sequence Clusters UniGene:75782 (1)
    Sequence Information (all 28)
    OTHER mstnb GENE PAGES
  • Alliance (1)
  • Gene:798441 (1)
  • VEGA:OTTDARG00000020932 (1)
  • Ensembl(GRCz11):ENSDARG00000069133 (1)
  • ORTHOLOGY for mstnb (Chr: 9)
    CITATIONS (66)