Gene

psmb8a

ID
ZDB-GENE-990415-141
Name
proteasome 20S subunit beta 8A
Symbol
psmb8a Nomenclature History
Previous Names
  • lmp7
  • psmb8
  • psmb8a (1)
  • beta5ia (1)
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have endopeptidase activity. Predicted to be involved in proteasomal ubiquitin-independent protein catabolic process and proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to localize to cytoplasm; nucleus; and proteasome core complex. Human ortholog(s) of this gene implicated in JMP syndrome. Orthologous to human PSMB8 (proteasome 20S subunit beta 8).
Genome Resources
Note
None
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With psmb8a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
JMP syndrome Alliance Proteasome-associated autoinflammatory syndrome 1 and digenic forms 256040
Associated With psmb8a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR016050 Proteasome beta-type subunit, conserved site
Family IPR000243 Peptidase T1A, proteasome beta-subunit
Family IPR001353 Proteasome, subunit alpha/beta
Family IPR023333 Proteasome B-type subunit
Family IPR035705 Proteasome subunit beta type 8
Homologous_superfamily IPR029055 Nucleophile aminohydrolases, N-terminal
Domain Details Per Protein
Protein Length Nucleophile aminohydrolases, N-terminal Peptidase T1A, proteasome beta-subunit Proteasome beta-type subunit, conserved site Proteasome B-type subunit Proteasome, subunit alpha/beta Proteasome subunit beta type 8
UniProtKB:O57330 271
UniProtKB:I3ISW4 84
UniProtKB:Q6NZ73 271
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations