ZFIN ID: ZDB-GENE-980526-265
Gene Name: myogenin
Gene Symbol: myog    Nomenclature History

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Previous Names: cb553 (1), Myf4 (1), zgc:100763

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including positive regulation of myoblast fusion; response to activity; and skeletal muscle tissue regeneration. Predicted to localize to nucleus. Is expressed in several structures, including mesoderm; musculature system; myoblast; post-vent region; and trunk. Orthologous to human MYOG (myogenin).
Genome Resources: Alliance (1),  Gene:30200 (1),  Ensembl(GRCz11):ENSDARG00000009438 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh265 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • kg125 Small Deletion Unknown Unknown CRISPR
    kg128 Insertion Unknown Unknown CRISPR
    myog_unrecovered Point Mutation Unknown Unknown ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-myog 1
    MO1-myog N/A 3
    MO2-myog N/A 1
    DISEASE ASSOCIATED WITH myog HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH myog VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to activity (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    aberrant processed transcript myog-202 (1)    Ensembl 846
    mRNA myog-201 (1)    Ensembl 1387
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-myog polyclonal IgG Rabbit IHC Santa Cruz Biotechnology, Inc.
    6
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM myog
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(myog-Hsa.HIST1H2BJ:mRFP) myog mRFP Danio rerioHomo sapiens 1 2
    Tg(myog:EGFP) myog EGFP Danio rerio 1 1
    MARKER RELATIONSHIPS
    myog Contained in: [BAC] CH211-86H15 (1)
    myog Encodes: [EST] cb553 (1) (order this), fb80e04 (1) (order this)
    [cDNA] MGC:100763 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131006 (1) 1384 nt
    Genomic GenBank:BX537143 (1) 204606 nt Blast at MegaBLAST
    Polypeptide UniProtKB:B0S6I5 (1) 256 aa
    Sequence Information (all 19)
    ORTHOLOGY for myog ( Chr: 11 )
    CITATIONS (143)