ZFIN ID: ZDB-GENE-080513-4
Gene Name: BCAR3 adaptor protein, NSP family member
Gene Symbol: bcar3    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have guanyl-nucleotide exchange factor activity. Predicted to be involved in positive regulation of peptidyl-serine phosphorylation. Orthologous to human BCAR3 (BCAR3 adaptor protein, NSP family member).
Genome Resources: Alliance (1),  Gene:570610 (1),  Ensembl(GRCz11):ENSDARG00000016981 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la016263Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la029427Tg Transgenic Insertion Unknown Unknown DNA
    la029428Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17906 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44681 Point Mutation Unknown Unknown ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH bcar3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH bcar3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process signal transduction (more)
    Molecular Function guanyl-nucleotide exchange factor activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000980 SH2 domain
    Domain IPR001660 Sterile alpha motif domain
    Domain IPR001895 Ras guanine-nucleotide exchange factors catalytic domain
    Homologous_superfamily IPR013761 Sterile alpha motif/pointed domain superfamily
    Homologous_superfamily IPR023578 Ras guanine nucleotide exchange factor domain superfamily
    Family IPR028849 Breast cancer anti-estrogen resistance protein 3
    Homologous_superfamily IPR036860 SH2 domain superfamily
    Homologous_superfamily IPR036964 Ras guanine-nucleotide exchange factor catalytic domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA bcar3-202 (1)    Ensembl 655
    bcar3-203 (1)    Ensembl 2693
    bcar3-204 (1)    Ensembl 537
    bcar3-205 (1)    Ensembl 2390
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM bcar3 No data available
    MARKER RELATIONSHIPS
    bcar3 Contained in: [BAC] CH211-80A15 (1), DKEY-7O6 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001113620 (1)
    Genomic GenBank:BX005425 (1) 252440 bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1R3Z4 (1) 918 aa
    Sequence Information (all 26)
    ORTHOLOGY for bcar3 ( Chr: 8 )
    CITATIONS (20)