ZFIN is now using GRCz12tu for Genomic Data
Gene
mknk1
- ID
- ZDB-GENE-080220-11
- Name
- MAPK interacting serine/threonine kinase 1
- Symbol
- mknk1 Nomenclature History
- Previous Names
-
- zgc:171912
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable calcium-dependent protein serine/threonine kinase activity; calcium/calmodulin-dependent protein kinase activity; and calmodulin binding activity. Predicted to be involved in intracellular signal transduction. Predicted to act upstream of or within protein phosphorylation and regulation of translation. Predicted to be active in cytoplasm and nucleus. Orthologous to human MKNK1 (MAPK interacting serine/threonine kinase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Family | IPR050205 | Calcium-dependent Serine/Threonine Protein Kinases |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Calcium-dependent Serine/Threonine Protein Kinases | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2B2B7 | InterPro | 461 | |||||
| UniProtKB:A0A8M2B223 | InterPro | 490 | |||||
| UniProtKB:F1QJV2 | InterPro | 459 | |||||
| UniProtKB:A0A8M2B1Y9 | InterPro | 488 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers