Gene

traf1

ID
ZDB-GENE-071120-4
Name
TNF receptor-associated factor 1
Symbol
traf1 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have tumor necrosis factor receptor binding activity and ubiquitin protein ligase binding activity. Predicted to be involved in protein K63-linked ubiquitination; regulation of intracellular signal transduction; and tumor necrosis factor-mediated signaling pathway. Predicted to localize to cytoplasmic side of plasma membrane and plasma membrane signaling receptor complex. Orthologous to human TRAF1 (TNF receptor associated factor 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With traf1 Human Ortholog
No data available
Associated With traf1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017907 Zinc finger, RING-type, conserved site
Domain IPR001293 Zinc finger, TRAF-type
Domain IPR001841 Zinc finger, RING-type
Domain IPR002083 MATH/TRAF domain
Domain IPR032070 TNF receptor-associated factor, BIRC3 binding domain
Domain IPR037306 TNF receptor-associated factor 1, MATH domain
Family IPR012227 TNF receptor-associated factor TRAF, metazoa
Family IPR027136 TNF receptor-associated factor 1
Family IPR043211 TNF receptor-associated factor TRAF
Homologous_superfamily IPR008974 TRAF-like
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Domain Details Per Protein
Protein Length MATH/TRAF domain TNF receptor-associated factor 1 TNF receptor-associated factor 1, MATH domain TNF receptor-associated factor, BIRC3 binding domain TNF receptor-associated factor TRAF TNF receptor-associated factor TRAF, metazoa TRAF-like Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-type Zinc finger, RING-type, conserved site Zinc finger, TRAF-type
UniProtKB:B0UXK1 551
UniProtKB:B0UXK3 293
UniProtKB:F1QDI5 298
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations