ZFIN ID: ZDB-GENE-070615-38
Gene Name: protein tyrosine phosphatase receptor type Db
Gene Symbol: ptprdb    Nomenclature History

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Previous Names: ptprd, zgc:165626

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation and synaptic membrane adhesion. Predicted to localize to the integral component of membrane. Is expressed in Rohon-Beard neurons; lateral line ganglion; olfactory placode; and trigeminal ganglion. Orthologous to human PTPRD (protein tyrosine phosphatase receptor type D).
Genome Resources: Alliance (1),  Gene:100073332 (1),  Ensembl(GRCz11):ENSDARG00000019945 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la013588Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa450 Point Mutation Unknown Splice Site ENU
    sa6579 Point Mutation Unknown Premature Stop ENU
    sa10181 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14902 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16499 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19467 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19468 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19469 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32644 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32645 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32646 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39591 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko364a Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-ptprdb 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ptprdb HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ptprdb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dephosphorylation (more)
    Cellular Component integral component of membrane (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Active_site IPR016130 Protein-tyrosine phosphatase, active site
    Domain IPR000242 PTP type protein phosphatase
    Domain IPR000387 Tyrosine specific protein phosphatases domain
    Domain IPR003595 Protein-tyrosine phosphatase, catalytic
    Domain IPR003598 Immunoglobulin subtype 2
    Domain IPR003599 Immunoglobulin subtype
    Domain IPR003961 Fibronectin type III
    Domain IPR007110 Immunoglobulin-like domain
    Domain IPR013098 Immunoglobulin I-set
    Homologous_superfamily IPR013783 Immunoglobulin-like fold
    Homologous_superfamily IPR029021 Protein-tyrosine phosphatase-like
    Homologous_superfamily IPR036116 Fibronectin type III superfamily
    Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ptprdb-201 (1)    Ensembl 1140
    ptprdb-202 (1)    Ensembl 6806
    ptprdb-203 (1)    Ensembl 957
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ptprdb No data available
    MARKER RELATIONSHIPS
    ptprdb Contained in: [BAC] DKEY-46O4 (1) (order this), DKEYP-118A3 (1)
    ptprdb Encodes: [cDNA] MGC:165626 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001166048 (1) 5805 nt
    Genomic GenBank:BX546494 (1) 174501 nt
    Select Tool
    Polypeptide UniProtKB:B8A5J5 (1) 1934 aa
    Sequence Information (all 64)
    ORTHOLOGY for ptprdb ( Chr: 1 )
    CITATIONS (29)