ZFIN ID: ZDB-GENE-070112-452
Gene Name: CD276 molecule
Gene Symbol: cd276    Nomenclature History

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Previous Names: sc:d0645, zgc:158279 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have signaling receptor binding activity. Predicted to be involved in T cell receptor signaling pathway. Predicted to localize to the external side of plasma membrane. Is expressed in several structures, including central nervous system; mesoderm; notochord; pronephric duct; and swim bladder bud. Orthologous to human CD276 (CD276 molecule).
Genome Resources: Alliance (1),  Gene:791140 (1),  Ensembl(GRCz11):ENSDARG00000003061 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la013330Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1379 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa2948 Point Mutation Unknown Splice Site ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cd276 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cd276 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of cytokine production (more)
    Cellular Component integral component of membrane (more)
    Molecular Function signaling receptor binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR003599 Immunoglobulin subtype
    Domain IPR007110 Immunoglobulin-like domain
    Domain IPR013106 Immunoglobulin V-set domain
    Domain IPR013162 CD80-like, immunoglobulin C2-set
    Homologous_superfamily IPR013783 Immunoglobulin-like fold
    Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cd276-202 (1)    Ensembl 491
    cd276-203 (1)    Ensembl 2136
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-cd276 monoclonal Mouse IHC 1
    CONSTRUCTS WITH SEQUENCES FROM cd276 No data available
    MARKER RELATIONSHIPS
    cd276 Contained in: [BAC] CH73-116F3 (1)
    [Fosmid] CH1073-312B22 (1)
    cd276 Encodes: [EST] cssl:d0645 (1)
    [cDNA] cssl:d163 (1), MGC:158279 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001080622 (1) 2169 nt
    Genomic GenBank:CU896640 (1) 114537 nt
    Select Tool
    Polypeptide UniProtKB:A1L1R8 (1) 300 aa
    Sequence Information (all 22)
    ORTHOLOGY for cd276 ( Chr: 18 )
    CITATIONS (29)