ZFIN ID: ZDB-GENE-050506-61
Gene Name: vinculin a
Gene Symbol: vcla
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: vcl, hm:zehn2160, im:6902790

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 9 figures from 5 publications
Directly Submitted Expression Data: 4 figures (7 images) from Thisse et al., 2004 [IMAGE:6902790]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Adult (90d-730d, breeding adult)
  anatomical structure, heart, lens, myotome (all 9) expand
Curated Microarray Expression: GEO (1)
PHENOTYPE
Data: 3 figures from 2 publications
Observed in: blood, blood circulation, cardiac muscle cell action potential, heart (all 8) expand
DISEASE ASSOCIATED WITH vcla HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
dilated cardiomyopathy 1W Cardiomyopathy, dilated, 1W 611407
hypertrophic cardiomyopathy 15 Cardiomyopathy, hypertrophic, 15 613255
GENE ONTOLOGY
Ontology GO Term
Biological Process heart contraction (more)
Cellular Component actin cytoskeleton (more)
Molecular Function actin binding (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000633 (1)
  • InterPro:IPR006077 (1)
  • InterPro:IPR017997 (1)
  • InterPro:IPR036723 (1)
  • PROSITE:PS00663 (1)
  • PROSITE:PS00664 (1)
  • Pfam:PF01044 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA vcla-001 (1) 4069
    ncRNA vcla-002 (1) 491
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Ab6-vcl (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM vcla No data available
    MARKER RELATIONSHIPS
    vclaContained in: [BAC] DKEY-188I15 (1) (order this), DKEY-231F24 (1) (order this), DKEY-252G6 (1) (order this)
    vclaEncodes: [EST] IMAGE:6902790 (1) (order this), zehn2160
    [cDNA] MGC:194417 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001128681 (1) 3540bp
    Genomic GenBank:CR788251 (1) 150523bp
    Select Tool
    Polypeptide UniProtKB:B3DI32 (1) 1131aa
    Sequence Clusters UniGene:78221 (1)
    Sequence Information (all 31)
    OTHER vcla GENE PAGES
  • Alliance (1)
  • Gene:552980 (1)
  • VEGA:OTTDARG00000027752 (1)
  • Ensembl(GRCz10):ENSDARG00000044968 (1)
  • ORTHOLOGY for vcla (Chr: 13)
    CITATIONS (27)