ZFIN ID: ZDB-GENE-050417-327
Gene Name: eukaryotic translation elongation factor 1 alpha 1b
Gene Symbol: eef1a1b    Nomenclature History

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Previous Names: eef1a1, wu:fj34g08, zgc:110335

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have GTPase activity and translation elongation factor activity. Predicted to be involved in translational elongation. Orthologous to several human genes including EEF1A1 (eukaryotic translation elongation factor 1 alpha 1).
Genome Resources: Alliance (1),  Gene:100004503 (1),  Ensembl(GRCz11):ENSDARG00000069951 (1)
GENE EXPRESSION
All Expression Data: Fig. S1 from Clark et al., 2011
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb99 Indel Unknown Unknown CRISPR
mn0137Gt Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11028 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18700 Point Mutation Unknown Premature Stop ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-eef1a1b,eef1a1l2 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH eef1a1b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH eef1a1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process translation (more)
    Molecular Function GTPase activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000795 Transcription factor, GTP-binding domain
    Domain IPR004160 Translation elongation factor EFTu/EF1A, C-terminal
    Domain IPR004161 Translation elongation factor EFTu-like, domain 2
    Family IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal
    Homologous_superfamily IPR009000 Translation protein, beta-barrel domain superfamily
    Homologous_superfamily IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
    Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
    Conserved_site IPR031157 Tr-type G domain, conserved site
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA eef1a1b-203 (1)    Ensembl 2224
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM eef1a1b No data available
    MARKER RELATIONSHIPS
    eef1a1b Contained in: [BAC] CH211-269I23 (1)
    eef1a1b Encodes: [EST] fj34g08
    [cDNA] MGC:110335 (1), MGC:173684 (1), MGC:192680 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001017795 (1) 2127 bp
    Genomic GenBank:BX005350 (1) 195436 bp
    Select Tool
    Polypeptide UniProtKB:A8WGK7 (1) 462 aa
    Sequence Information (all 16)
    ORTHOLOGY for eef1a1b ( Chr: 1 )
    CITATIONS (31)