ZFIN ID: ZDB-GENE-030131-8278
Gene Name: eukaryotic translation elongation factor 1 alpha 1a
Gene Symbol: eef1a1a    Nomenclature History

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Previous Names: fj64c02, wu:fj64c02, zgc:73138

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have GTPase activity and translation elongation factor activity. Involved in heart development. Is expressed in asteriscus. Orthologous to several human genes including EEF1A1 (eukaryotic translation elongation factor 1 alpha 1).
Genome Resources: Alliance (1),  Gene:336334 (1),  Ensembl(GRCz11):ENSDARG00000039502 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH eef1a1a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH eef1a1a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process heart development (more)
Molecular Function GTPase activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Conserved_site IPR031157 Tr-type G domain, conserved site
Domain IPR000795 Transcription factor, GTP-binding domain
Domain IPR004160 Translation elongation factor EFTu/EF1A, C-terminal
Domain IPR004161 Translation elongation factor EFTu-like, domain 2
Family IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal
Homologous_superfamily IPR009000 Translation protein, beta-barrel domain superfamily
Homologous_superfamily IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA eef1a1a-201 (1)    Ensembl 923
eef1a1a-202 (1)    Ensembl 2170
ncRNA eef1a1a-003 (1)    Ensembl 491
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM eef1a1a
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
tg(ma-gfp,eef1a1a:mcherry) eef1a1a GFPMAmCherry Danio rerio 1 1
MARKER RELATIONSHIPS
eef1a1a Contained in: [BAC] DKEY-187A12 (1) (order this)
eef1a1a Encodes: [EST] fj64c02
[cDNA] MGC:73138 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_200009 (1) 2172 nt
Genomic GenBank:BX323884 (1) 137509 nt
Select Tool
Polypeptide UniProtKB:Q6P969 (1) 462 aa
Sequence Information (all 15)
ORTHOLOGY for eef1a1a ( Chr: 13 )
CITATIONS (27)