ZFIN ID: ZDB-GENE-050417-118
Gene Name: aldo-keto reductase family 1, member A1b (aldehyde reductase)
Gene Symbol: akr1a1b
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:110225 (1)

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(Including Attributions)
Location: Chr: 6 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have alditol:NADP+ 1-oxidoreductase activity; predicted to be involved in oxidation-reduction process; orthologous to human AKR1A1 (aldo-keto reductase family 1 member A1).
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:110225]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7154417]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la025507Tg Transgenic Insertion Unknown Unknown DNA
la025508Tg Transgenic Insertion Unknown Unknown DNA
PHENOTYPE No data available
DISEASE ASSOCIATED WITH akr1a1b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH akr1a1b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cellular detoxification of aldehyde (more)
Cellular Component apical plasma membrane (more)
Molecular Function NOT retinol dehydrogenase activity (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR018170 (1)
  • InterPro:IPR020471 (1)
  • InterPro:IPR023210 (1)
  • InterPro:IPR036812 (1)
  • PROSITE:PS00062 (1)
  • PROSITE:PS00063 (1)
  • PROSITE:PS00798 (1)
  • Pfam:PF00248 (1)
  • EC:1.1.1.2 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA akr1a1b-007 (1) 877
    mRNA akr1a1b-201 (1) 754
    akr1a1b-202 (1) 1091
    akr1a1b-203 (1) 910
    akr1a1b-204 (1) 760
    akr1a1b-205 (1) 1182
    akr1a1b-207 (1) 803
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM akr1a1b No data available
    MARKER RELATIONSHIPS
    akr1a1bContained in: [BAC] CH211-175H18 (1) (order this)
    akr1a1bEncodes: [EST] IMAGE:7154417 (1) (order this)
    [cDNA] MGC:110225 (1) (order this), MGC:174295 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001017640 (1) 1160bp
    Genomic GenBank:CR854855 (1) 144317bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8QTH3 (1) 326aa
    Sequence Clusters UniGene:83969 (1)
    Sequence Information (all 29)
    OTHER akr1a1b GENE PAGES
  • Alliance (1)
  • Gene:799805 (1)
  • VEGA:OTTDARG00000021982 (1)
  • ORTHOLOGY for akr1a1b (Chr: 6)
    CITATIONS (22)