ZFIN ID: ZDB-GENE-050417-118
Gene Name: aldo-keto reductase family 1, member A1b (aldehyde reductase)
Gene Symbol: akr1a1b    Nomenclature History

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Previous Name: zgc:110225 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have alditol:NADP+ 1-oxidoreductase activity. Predicted to be involved in aldehyde catabolic process; carboxylic acid metabolic process; and cellular detoxification of aldehyde. Predicted to localize to apical plasma membrane and cytosol. Orthologous to human AKR1A1 (aldo-keto reductase family 1 member A1).
Genome Resources: Alliance (1),  Gene:799805 (1),  Ensembl(GRCz11):ENSDARG00000052030 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:110225]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7154417]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la025507Tg Transgenic Insertion Unknown Unknown DNA
la025508Tg Transgenic Insertion Unknown Unknown DNA
PHENOTYPE No data available
DISEASE ASSOCIATED WITH akr1a1b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH akr1a1b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cellular detoxification of aldehyde (more)
Cellular Component apical plasma membrane (more)
Molecular Function NOT   retinol dehydrogenase activity (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA akr1a1b-201 (1)    Ensembl 754
akr1a1b-202 (1)    Ensembl 1091
akr1a1b-203 (1)    Ensembl 910
akr1a1b-204 (1)    Ensembl 760
akr1a1b-205 (1)    Ensembl 1182
akr1a1b-207 (1)    Ensembl 803
ncRNA akr1a1b-007 (1)    Ensembl 877
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM akr1a1b No data available
MARKER RELATIONSHIPS
akr1a1b Contained in: [BAC] CH211-175H18 (1)
akr1a1b Encodes: [EST] IMAGE:7154417 (1)
[cDNA] MGC:110225 (1), MGC:174295 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001017640 (1) 1160 nt
Genomic GenBank:CR854855 (1) 144317 nt
Select Tool
Polypeptide UniProtKB:A0A2R8QTH3 (1) 326 aa
Sequence Information (all 28)
ORTHOLOGY for akr1a1b ( Chr: 6 )
CITATIONS (26)