ZFIN ID: ZDB-GENE-050309-24
Gene Name: glutathione S-transferase mu tandem duplicate 3
Gene Symbol: gstm.3    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: gstm3, im:6897516

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Exhibits glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Is expressed in brain; gill; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including central nervous system cancer (multiple); eye disease (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); and lung disease (multiple). Orthologous to several human genes including GSTM1 (glutathione S-transferase mu 1); GSTM2 (glutathione S-transferase mu 2); and GSTM3 (glutathione S-transferase mu 3).
Genome Resources: Alliance (1),  Gene:568744 (1),  Ensembl(GRCz11):ENSDARG00000088116 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa31656 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gstm.3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH gstm.3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process glutathione metabolic process (more)
    Molecular Function glutathione transferase activity (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gstm.3-201 (1)    Ensembl 1603
    gstm.3-203 (1)    Ensembl 1001
    ncRNA gstm.3-003 (1)    Ensembl 1125
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gstm.3 No data available
    MARKER RELATIONSHIPS
    gstm.3 Contained in: [BAC] DKEY-183P4 (1) (order this)
    gstm.3 Encodes: [EST] IMAGE:6897516 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001162851 (1)
    Genomic GenBank:CR847543 (1) 207382 nt Blast at MegaBLAST
    Polypeptide UniProtKB:B8JIS5 (1) 219 aa
    Sequence Information (all 9)
    ORTHOLOGY for gstm.3 ( Chr: 8 )
    CITATIONS (25)