ZFIN ID: ZDB-GENE-050309-23
Gene Name: integrin, alpha 6a
Gene Symbol: itga6a
Sequence Ontology ID : SO:0000704

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Previous Names: itga6, fb80g02, im:6897425, si:dkey-32o22.1, wu:fb80g02

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Involved in skeletal muscle tissue development; predicted to localize to the integrin complex; orthologous to human ITGA6 (integrin subunit alpha 6).
GENE EXPRESSION
All Expression Data: 9 figures from 4 publications
Directly Submitted Expression Data: 6 figures (13 images) from Thisse et al., 2004 [IMAGE:6897425]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa18258 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21422 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 3 figures from Goody et al., 2012
    Observed in:
    DISEASE ASSOCIATED WITH itga6a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    junctional epidermolysis bullosa with pyloric atresia Epidermolysis bullosa, junctional, with pyloric stenosis 226730
    DISEASE ASSOCIATED WITH itga6a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process skeletal muscle tissue development (more)
    Cellular Component integral component of membrane (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000413 (1)
  • InterPro:IPR013517 (1)
  • InterPro:IPR013519 (1)
  • InterPro:IPR013649 (1)
  • InterPro:IPR018184 (1)
  • InterPro:IPR028994 (1)
  • InterPro:IPR032695 (1)
  • PROSITE:PS00242 (1)
  • PROSITE:PS51470 (1)
  • Pfam:PF01839 (1)
  • Pfam:PF08441 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cu469503.1-201 (1) 1274
    itga6a-201 (1) 3231
    itga6a-202 (1) 4057
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM itga6a No data available
    MARKER RELATIONSHIPS
    itga6aContained in: [BAC] CH211-245G15 (1) (order this), DKEY-251J19 (1) (order this)
    itga6aEncodes: [EST] fb80g02, IMAGE:6897425 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005167409 (1) 3505bp
    Genomic GenBank:CU469503 (1) 166759bp
    Select Tool
    Polypeptide UniProtKB:A8WHQ8 (1) 1092aa
    Sequence Clusters UniGene:117274 (1)
    Sequence Information (all 31)
    OTHER itga6a GENE PAGES
  • Alliance (1)
  • Gene:503893 (1)
  • VEGA:OTTDARG00000025531 (1)
  • VEGA:OTTDARG00000032744 (1)
  • Ensembl(GRCz11):ENSDARG00000042282 (2)
  • ORTHOLOGY for itga6a (Chr: 9)
    CITATIONS (21)