ZFIN ID: ZDB-GENE-050211-2
Gene Name: hypoxia inducible factor 1 subunit alpha, like 2
Gene Symbol: hif1al2    Nomenclature History

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Previous Names: hif1al (1), Hif2a (1), HIF3B (1), zgc:112119

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in several structures, including digestive system; gill; head; heart; and pleuroperitoneal region.
Genome Resources: Alliance (1),  Gene:497283 (1),  Ensembl(GRCz11):ENSDARG00000044550 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Gastrula:75%-epiboly (8.0h-9.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa23956 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH hif1al2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hif1al2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function protein dimerization activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hif1al2-201 (1)    Ensembl 2522
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    ab1-hif1al2 polyclonal Rabbit 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hif1al2 No data available
    MARKER RELATIONSHIPS
    hif1al2 Contained in: [BAC] DKEY-175M17 (1) (order this)
    hif1al2 Encodes: [cDNA] MGC:112119 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001012371 (1) 1572 nt
    Genomic GenBank:BX530031 (1) 160736 nt
    Select Tool
    Polypeptide UniProtKB:F1QQQ1 (1) 663 aa
    Sequence Information (all 18)
    ORTHOLOGY for hif1al2 ( Chr: 21 )
    CITATIONS (30)