ZFIN ID: ZDB-GENE-050202-4
Gene Name: protocadherin 1 alpha 4
Gene Symbol: pcdh1a4    Nomenclature History

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Previous Name: DrPcdh1ab2 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have calcium ion binding activity. Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to localize to integral component of membrane and plasma membrane.
Genome Resources: Alliance (1),  Gene:497127 (1),  Ensembl(GRCz11):ENSDARG00000097170 (1)
GENE EXPRESSION
All Expression Data: text only from Emond et al., 2008
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa21717 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21718 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa30651 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38794 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45403 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-pcdh1a N/A 1
    MO2-pcdh1a N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pcdh1a4 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pcdh1a4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell adhesion (more)
    Cellular Component integral component of membrane (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pcdh1a6-202 (1)    Ensembl 5406
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-pcdh1a polyclonal Rabbit IHC, WB 2
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pcdh1a4 No data available
    MARKER RELATIONSHIPS
    pcdh1a4 Contained in: [BAC] CH211-179J10 (1), DKEY-17C10 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001024099 (1) 5404 nt
    Genomic GenBank:BX119910 (1) 199662 nt
    Select Tool
    Polypeptide UniProtKB:E7F4G4 (1) 941 aa
    Sequence Information (all 12)
    ORTHOLOGY for pcdh1a4 ( Chr: 10 )
    CITATIONS (17)