ZFIN ID: ZDB-GENE-050201-1
Gene Name: tyrosine hydroxylase 2
Gene Symbol: th2
Sequence Ontology ID : SO:0000704

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(Including Attributions)
Location: Chr: 4 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 26 figures from 14 publications
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Adult (90d-730d, breeding adult)
  anatomical structure, brain, brain dopaminergic neuron, caudal hypothalamic zone neuron (all 28) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents: MO1-th2 (1), MO2-th2 (1), MO3-th2 (1), MO4-th2 (1), MO5-th2 (1)
PHENOTYPE
Data: 5 figures from 2 publications
Observed in: caudal hypothalamic zone neuron, head dopamine, head histamine, head (all 6) expand
DISEASE ASSOCIATED WITH th2 HUMAN ORTHOLOGNo data available
GENE ONTOLOGY
Ontology GO Term
Biological Process dopamine biosynthetic process (more)
Molecular Function tryptophan 5-monooxygenase activity (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001273 (1)
  • InterPro:IPR005962 (1)
  • InterPro:IPR018301 (1)
  • InterPro:IPR019773 (1)
  • InterPro:IPR019774 (1)
  • InterPro:IPR036329 (1)
  • InterPro:IPR036951 (1)
  • PROSITE:PS00367 (1)
  • PROSITE:PS51410 (1)
  • Pfam:PF00351 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA th2-001 (1) 1635
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Ab4-th (1), ab7-th (1), ab8-th (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM th2
    tg(th2:gal4-vp16), tg(th2:gfp-aequorin)
    MARKER RELATIONSHIPS
    th2Contained in: [BAC] CH211-260P3 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001001829 (1) 1635bp
    Genomic GenBank:BX510924 (1) 143251bp
    Select Tool
    Polypeptide UniProtKB:Q5RHI3 (1) 475aa
    Sequence Clusters UniGene:88913 (1)
    Sequence Information (all 14)
    OTHER th2 GENE PAGES
  • Alliance (1)
  • Gene:414844 (1)
  • VEGA:OTTDARG00000017748 (1)
  • Ensembl(GRCz10):ENSDARG00000038384 (1)
  • ORTHOLOGY for th2 (Chr: 4)
    CITATIONS (43)