ZFIN ID: ZDB-GENE-050201-1
Gene Name: tyrosine hydroxylase 2
Gene Symbol: th2
Sequence Ontology ID : SO:0000704

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(Including Attributions)
Location: Chr: 4 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 23 figures from 13 publications
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Adult (90d-730d, breeding adult)
  anatomical structure, brain, brain dopaminergic neuron, caudal parvocellular preoptic nucleus (all 26) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents: MO1-th2 (1), MO2-th2 (1), MO3-th2 (1), MO4-th2 (1), MO5-th2 (1)
PHENOTYPE
Data: 2 figures from Ren et al., 2013
Observed in: paraventricular organ neurotransmitter metabolic process, serotonin metabolic process
DISEASE ASSOCIATED WITH th2 HUMAN ORTHOLOGNo data available
GENE ONTOLOGY
Ontology GO Term
Biological Process serotonin biosynthetic process (more)
Molecular Function tryptophan 5-monooxygenase activity (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001273 (1)
  • InterPro:IPR005962 (1)
  • InterPro:IPR018301 (1)
  • InterPro:IPR019773 (1)
  • InterPro:IPR019774 (1)
  • PROSITE:PS00367 (1)
  • PROSITE:PS51410 (1)
  • Pfam:PF00351 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA th2-001 (1) 1635
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Ab4-th (1), ab7-th (1), ab8-th (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM th2
    tg(th2:gal4-vp16), tg(th2:gfp-aequorin)
    MARKER RELATIONSHIPS
    th2Contained in: [BAC] CH211-260P3 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001001829 (1) 1635bp
    Genomic GenBank:BX510924 (1) 143251bp
    Select Tool
    Polypeptide UniProtKB:Q5RHI3 (1) 475aa
    Sequence Clusters UniGene:88913 (1)
    Sequence Information (all 14)
    OTHER th2 GENE PAGES
  • Alliance (1)
  • Gene:414844 (1)
  • VEGA:OTTDARG00000017748 (1)
  • Ensembl(GRCz10):ENSDARG00000038384 (1)
  • ORTHOLOGY for th2 (Chr: 4)
    CITATIONS (42)