Gene
mllt10
- ID
- ZDB-GENE-041114-176
- Name
- MLLT10 histone lysine methyltransferase DOT1L cofactor
- Symbol
- mllt10 Nomenclature History
- Previous Names
-
- id:ibd5120
- wu:fe48f12
- zgc:92208 (1)
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have histone binding activity and nucleosome binding activity. Involved in canonical Wnt signaling pathway; cellular homeostasis; and intestinal epithelial structure maintenance. Predicted to localize to nucleus. Is expressed in brain; hindbrain; intestine; and midbrain. Human ortholog(s) of this gene implicated in acute monocytic leukemia and acute myeloid leukemia. Orthologous to human MLLT10 (MLLT10 histone lysine methyltransferase DOT1L cofactor).
- Genome Resources
- Note
- None
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- No data available
- Thisse Expression Data
-
- MGC:92208 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Mahmoudi et al., 2010
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
acute myeloid leukemia | Alliance | Leukemia, acute myeloid | 601626 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR019786 | Zinc finger, PHD-type, conserved site |
Domain | IPR001965 | Zinc finger, PHD-type |
Domain | IPR019787 | Zinc finger, PHD-finger |
Domain | IPR034732 | Extended PHD (ePHD) domain |
Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
Domain Details Per Protein
Protein | Length | Extended PHD (ePHD) domain | Zinc finger, FYVE/PHD-type | Zinc finger, PHD-finger | Zinc finger, PHD-type | Zinc finger, PHD-type, conserved site | Zinc finger, RING/FYVE/PHD-type |
---|---|---|---|---|---|---|---|
UniProtKB:A0A286YAM6
|
1089 | ||||||
UniProtKB:F8W2W1
|
1078 | ||||||
UniProtKB:A0A2R8RZV0
|
1059 | ||||||
UniProtKB:F8W451
|
1133 | ||||||
UniProtKB:Q5U394
|
352 | ||||||
UniProtKB:E7F6V1
|
1022 | ||||||
UniProtKB:F1RE24
|
352 | ||||||
UniProtKB:A0A2R8QE63
|
1051 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
mllt10-204
(1)
|
4589 nt | |
mRNA |
mllt10-206
(1)
|
6768 nt | |
mRNA |
mllt10-208
(1)
|
5383 nt | |
ncRNA |
mllt10-004
(1)
|
834 nt | |
ncRNA |
mllt10-005
(1)
|
840 nt | |
ncRNA |
mllt10-006
(1)
|
784 nt | |
ncRNA |
mllt10-007
(1)
|
714 nt | |
ncRNA |
mllt10-008
(1)
|
711 nt | |
ncRNA |
mllt10-009
(1)
|
849 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Gene Tree
- Ensembl