ZFIN ID: ZDB-GENE-041114-176
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Gene Name: MLLT10, histone lysine methyltransferase DOT1L cofactor
Gene Symbol: mllt10
Sequence Ontology ID : SO:0000704

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Previous Names: id:ibd5120, wu:fe48f12, zgc:92208 (1)

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(Including Attributions)
Location: Chr: 24 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 5 figures from 4 publications
Directly Submitted Expression Data: 2 figures (2 images) from Kudoh et al., 2001 [ibd5120]
  1 figure (1 image) from Thisse et al., 2004 [MGC:92208]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  brain, hindbrain, intestine, midbrain (all 5) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010007Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • la010998Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • la014516Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • la028600Tg Transgenic Insertion Unknown Unknown DNA
    Targeting reagents: MO1-mllt10 (1), MO2-mllt10 (1), MO3-mllt10 (1)
    PHENOTYPE
    Data: 3 figures from Mahmoudi et al., 2010
    Observed in: canonical Wnt signaling pathway, epithelial cell, intestinal epithelial structure maintenance, intestinal epithelium (all 6) expand
    DISEASE ASSOCIATED WITH mllt10 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    acute myeloid leukemia Leukemia, acute myeloid 601626
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process canonical Wnt signaling pathway (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001965
  • InterPro:IPR011011
  • InterPro:IPR013083
  • InterPro:IPR019786
  • InterPro:IPR019787
  • InterPro:IPR034732
    		•
  • PROSITE:PS01359
  • PROSITE:PS50016
  • PROSITE:PS51805
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA mllt10-001 (1) 4589
    Select Tool
    mllt10-002 (1) 5383
    Select Tool
    mllt10-003 (1) 6768
    Select Tool
    ncRNA mllt10-004 (1) 834
    Select Tool
    mllt10-005 (1) 840
    Select Tool
    mllt10-006 (1) 784
    Select Tool
    mllt10-007 (1) 714
    Select Tool
    mllt10-008 (1) 711
    Select Tool
    mllt10-009 (1) 849
    Select Tool
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM mllt10 No data available
    MARKER RELATIONSHIPS
    mllt10Contained in: [BAC] CH211-14G13 (1) (order this)
    mllt10Encodes: [EST] fe48f12, ibd5120 (order this)
    [cDNA] MGC:92208 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001007308 (1) 2859bp
    Select Tool
    Genomic GenBank:CR376737 (1) 158366bp
    Select Tool
    Polypeptide UniProtKB:F8W451 1133aa
    Select Tool
    Sequence Clusters UniGene:105604 (1)
    Sequence Information (all 45)
    OTHER mllt10 GENE PAGES
  • Gene:492342 (1)
  • VEGA:OTTDARG00000022481 (1)
  • Ensembl(GRCz10):ENSDARG00000045401 (1)
    • ORTHOLOGY for mllt10 (Chr: 24)
    CITATIONS (20)