ZFIN ID: ZDB-GENE-041011-1
Gene Name: lin-7 homolog B (C. elegans)
Gene Symbol: lin7b    Nomenclature History

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Previous Names: fj41b11, fj63g03, wu:fj41b11, wu:fj63g03, zgc:109997

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have L27 domain binding activity. Predicted to be involved in maintenance of epithelial cell apical/basal polarity; neurotransmitter secretion; and protein localization to basolateral plasma membrane. Predicted to localize to MPP7-DLG1-LIN7 complex; basolateral plasma membrane; and synapse. Is expressed in brain; central nervous system; eye; and retinal inner nuclear layer. Orthologous to human LIN7B (lin-7 homolog B, crumbs cell polarity complex component).
Genome Resources: Alliance (1),  Gene:553768 (1),  Ensembl(GRCz11):ENSDARG00000037932 (2)
GENE EXPRESSION
All Expression Data: 10 figures from 3 publications
Directly Submitted Expression Data: 6 figures (7 images) from Thisse et al., 2004 [MGC:109997]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-lin7b
2
PHENOTYPE No data available
DISEASE ASSOCIATED WITH lin7b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH lin7b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process exocytosis (more)
Cellular Component cell junction (more)
Molecular Function L27 domain binding (more)
GO Terms (all 14)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA lin7b-201 (1)    Ensembl 1587
lin7b-202 (1)    Ensembl 1425
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-lin7 polyclonal Rabbit IHC, WB 6
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM lin7b No data available
MARKER RELATIONSHIPS
lin7b Contained in: [BAC] DKEY-15N1 (1) (order this)
lin7b Encodes: [EST] fj41b11 (1), fj63g03 (1)
[cDNA] MGC:109997 (1), MGC:192979 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001020733 (1) 1558 nt
Genomic GenBank:BX324157 (1) 272769 nt Blast at MegaBLAST
Polypeptide UniProtKB:F1RDK3 (1) 220 aa
Sequence Information (all 21)
ORTHOLOGY for lin7b ( Chr: 3 )
CITATIONS (26)