ZFIN ID: ZDB-GENE-040426-1665
Gene Name: lin-7 homolog A (C. elegans)
Gene Symbol: lin7a    Nomenclature History

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Previous Name: zgc:73090

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have L27 domain binding activity. Predicted to be involved in maintenance of epithelial cell apical/basal polarity; neurotransmitter secretion; and protein localization to basolateral plasma membrane. Predicted to localize to MPP7-DLG1-LIN7 complex; basolateral plasma membrane; and synapse. Is expressed in myotome and nervous system. Orthologous to human LIN7A (lin-7 homolog A, crumbs cell polarity complex component).
Genome Resources: Alliance (1),  Gene:393682 (1),  Ensembl(GRCz11):ENSDARG00000013414 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6051 Point Mutation Unknown Premature Stop ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH lin7a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH lin7a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process exocytosis (more)
Cellular Component cell junction (more)
Molecular Function L27 domain binding (more)
GO Terms (all 14)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA lin7a-201 (1)    Ensembl 2723
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-lin7 polyclonal Rabbit IHC, WB 6
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM lin7a No data available
MARKER RELATIONSHIPS
lin7a Contained in: [BAC] CH211-91G3 (1), DKEY-231A18 (1) (order this)
lin7a Encodes: [cDNA] MGC:73090 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_200709 (1) 2129 nt
Genomic GenBank:BX537308 (1) 191880 nt
Select Tool
Polypeptide UniProtKB:Q6PC63 (1) 218 aa
Sequence Information (all 13)
ORTHOLOGY for lin7a ( Chr: 4 )
CITATIONS (24)