ZFIN Gene: uxt

ZFIN ID: ZDB-GENE-040912-118

ZFIN ID: ZDB-GENE-040912-118

Gene Name:

ubiquitously-expressed, prefoldin-like chaperone

Gene Symbol:

uxt

Sequence Ontology ID :

SO:0001217

Previous Name:

zgc:101894

Location:

Chr: 8 Mapping Details/Browsers

Nomenclature History

AUTOMATED DESCRIPTION

Predicted to have beta-tubulin binding activity and transcription corepressor activity. Involved in angiogenesis and negative regulation of Notch signaling pathway. Localizes to the chromatin. ...

GENE EXPRESSION
All Expression Data:	3 figures from 2 publications
Directly Submitted Expression Data:	1 figure (1 image) from Thisse et al., 2004 [MGC:101894]
Wild-type Stages, Structures:	Zygote:1-cell (0.0h-0.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
	head trunk whole organism

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
sa8704	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa21201	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa21202	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)

Targeting reagents:

PHENOTYPE

Data:	7 figures from Zhou et al., 2015
Observed in:	caudal fin dorsal longitudinal anastomotic vessel blood vessel development endothelial tip cell blood vessel endothelial cell migration hindbrain intersegmental vessel angiogenesis intersegmental vessel blood vessel endothelial cell intersegmental vessel Notch signaling pathway trunk trunk vasculature artery trunk vasculature whole organism

DISEASE ASSOCIATED WITH uxt HUMAN ORTHOLOG No data available

DISEASE ASSOCIATED WITH uxt VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	angiogenesis (more)
Cellular Component	chromatin (more)
Molecular Function	transcription corepressor activity (more)

GO Terms (all 13)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR003994 (1) InterPro:IPR004127 (1) InterPro:IPR009053 (1) InterPro:IPR011599 (1)	Pfam:PF02996 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	uxt-201 (1)	860	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
aberrant processed transcript	uxt-202 (1)	996	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

GENE PRODUCT DESCRIPTION No description available

INTERACTIONS AND PATHWAYS

ANTIBODIES

Ab1-uxt (1)

PLASMIDS No data available

CONSTRUCTS WITH SEQUENCES FROM uxt No data available

MARKER RELATIONSHIPS

uxt Contained in:	[BAC] CH211-257I15 (1) (order this)
uxt Encodes:	[cDNA] MGC:101894 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_001004671 (1)	875 bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CR356245 (1)	153042 bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:Q66IA7 (1)	155 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast
Sequence Clusters	UniGene:90415 (1)

Sequence Information (all 10)

OTHER uxt GENE PAGES

Alliance (1)

Gene:447933 (1)

VEGA:OTTDARG00000022073 (1)

Ensembl(GRCz11):ENSDARG00000019339 (2)

ORTHOLOGY for uxt ( Chr: 8 )

CITATIONS (17)

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