ZFIN ID: ZDB-GENE-040718-32
Gene Name: guanylate binding protein 1
Gene Symbol: gbp1    Nomenclature History

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Previous Names: wu:fd36d06, zgc:92185 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have GTP binding activity and GTPase activity. Orthologous to human GBP1 (guanylate binding protein 1) and GBP4 (guanylate binding protein 4).
Genome Resources: Alliance (1),  Gene:436615 (1),  Ensembl(GRCz11):ENSDARG00000038668 (2)
GENE EXPRESSION
All Expression Data: Fig. 2 from Sieger et al., 2009
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH gbp1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH gbp1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Molecular Function GTPase activity (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR003191 Guanylate-binding protein/Atlastin, C-terminal
Domain IPR015894 Guanylate-binding protein, N-terminal
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain IPR030386 GB1/RHD3-type guanine nucleotide-binding (G) domain
Homologous_superfamily IPR036543 Guanylate-binding protein, C-terminal domain superfamily
Domain IPR037684 Guanylate-binding protein, C-terminal
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA gbp1-201 (1)    Ensembl 2343
gbp1-203 (1)    Ensembl 650
ncRNA gbp1-003 (1)    Ensembl 775
gbp1-004 (1)    Ensembl 902
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM gbp1 No data available
MARKER RELATIONSHIPS
gbp1 Contained in: [BAC] DKEY-97A13 (1) (order this)
gbp1 Encodes: [EST] fd36d06
[cDNA] MGC:92185 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001002343 (1) 2361 bp
Genomic GenBank:BX663525 (1) 261927 bp Blast at MegaBLAST
Polypeptide UniProtKB:Q6DHP7 (1) 621 aa
Sequence Information (all 15)
ORTHOLOGY for gbp1 ( Chr: 2 )
CITATIONS (24)