ZFIN ID: ZDB-GENE-040718-178
Gene Name: NK6 homeobox 1
Gene Symbol: nkx6.1
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:92879

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(Including Attributions)
Location: Chr: 21 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA-binding activity transcription factor activity and sequence-specific DNA binding activity; involved in several processes, including animal organ development, animal organ  ...
GENE EXPRESSION
All Expression Data: 41 figures from 28 publications
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa3108 Point Mutation Unknown Splice Site ENU
ulg005 Small Deletion Unknown Frameshift, Premature Stop CRISPR
Targeting reagents:
PHENOTYPE
Data: 6 figures from 4 publications
Observed in:
DISEASE ASSOCIATED WITH nkx6.1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH nkx6.1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process endocrine pancreas development (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 14)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000047 (1)
  • InterPro:IPR001356 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR020479 (1)
  • InterPro:IPR033630 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nkx6.1-201 (1) 2023
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM nkx6.1
    MARKER RELATIONSHIPS
    nkx6.1Contained in: [BAC] CH211-203L7 (1) (order this)
    nkx6.1Encodes: [cDNA] MGC:92879 (1) (order this), MGC:191271 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002475 (1) 2045bp
    Genomic GenBank:BX000991 (1) 170966bp
    Select Tool
    Polypeptide UniProtKB:F1QUC3 (1) 312aa
    Sequence Clusters UniGene:79658 (1)
    Sequence Information (all 17)
    OTHER nkx6.1 GENE PAGES
  • Alliance (1)
  • Gene:436748 (1)
  • VEGA:OTTDARG00000020995 (1)
  • Ensembl(GRCz11):ENSDARG00000022569 (2)
  • ORTHOLOGY for nkx6.1 (Chr: 21)
    CITATIONS (60)