Gene

gtf2f2a

ID

ZDB-GENE-040625-131

Name

general transcription factor IIF, polypeptide 2a

Symbol

gtf2f2a Nomenclature History

Previous Names

gtf2f2
wu:fb39a05
zgc:86775

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to have ATP binding activity; DNA binding activity; and DNA helicase activity. Predicted to be involved in positive regulation of transcription elongation from RNA polymerase II promoter and positive regulation of transcription initiation from RNA polymerase II promoter. Predicted to localize to transcription factor TFIIF complex. Orthologous to human GTF2F2 (general transcription factor IIF subunit 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6893176 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gtf2f2a Human Ortholog

No data available

Associated With gtf2f2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR040450	TFIIF beta subunit, HTH domain
Domain	IPR040504	TFIIF, beta subunit, N-terminal
Family	IPR003196	Transcription initiation factor IIF, beta subunit
Homologous_superfamily	IPR011039	Transcription Factor IIF, Rap30/Rap74, interaction
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Homologous_superfamily	IPR036390	Winged helix DNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	TFIIF beta subunit, HTH domain	TFIIF, beta subunit, N-terminal	Transcription Factor IIF, Rap30/Rap74, interaction	Transcription initiation factor IIF, beta subunit	Winged helix DNA-binding domain superfamily	Winged helix-like DNA-binding domain superfamily
UniProtKB:A7MCQ3 InterPro	249
UniProtKB:B8JHR3 InterPro	265

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	gtf2f2a-201 (1) Ensembl	Ensembl	1,072 nt	Select Tool
mRNA	gtf2f2a-202 (1) Ensembl	Ensembl	1,255 nt	Select Tool
mRNA	gtf2f2a-203 (1) Ensembl	Ensembl	909 nt	Select Tool
mRNA	gtf2f2a-205 (1) Ensembl	Ensembl	1,139 nt	Select Tool
ncRNA	gtf2f2a-003 (1) Ensembl	Ensembl	721 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations