ZFIN ID: ZDB-GENE-040426-2500
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.
Gene Name: ligand of numb-protein X 2b
Gene Symbol: lnx2b
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: lnx-l (1), id:ibd3184, lnx-like (1), zgc:85925 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 6 figures from 5 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:85925]
  2 figures (3 images) from Kudoh et al., 2001 [ibd3184]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010014Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • la012572Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • la018980Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • la018981Tg Transgenic Insertion Unknown Unknown DNA
    la027546Tg Transgenic Insertion Unknown Unknown DNA
    Targeting reagents:
    PHENOTYPE
    Data: 3 figures from Ro et al., 2009
    Observed in:
    DISEASE ASSOCIATED WITH lnx2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH lnx2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein K48-linked ubiquitination (more)
    Cellular Component cellular_component (more)
    Molecular Function ubiquitin-protein transferase activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001478 (1)
  • InterPro:IPR001841 (1)
  • InterPro:IPR013083 (1)
  • InterPro:IPR017907 (1)
  • InterPro:IPR027370 (1)
  • InterPro:IPR036034 (1)
    		•
  • PROSITE:PS00518 (1)
  • PROSITE:PS50089 (1)
  • PROSITE:PS50106 (1)
    		•
  • Pfam:PF00595 (1)
  • Pfam:PF13445 (1)
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lnx2b-001 (1) 3150
    Select Tool
    ncRNA lnx2b-002 (1) 394
    Select Tool
    mRNA lnx2b-003 (1) 572
    Select Tool
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM lnx2b No data available
    MARKER RELATIONSHIPS
    lnx2bContained in: [BAC] CH211-231B5 (1) (order this), CH211-276G21 (1) (order this)
    lnx2bEncodes: [EST] ibd3184 (1) (order this)
    [cDNA] MGC:85925 (1) (order this), MGC:162185 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212940 (1) 3201bp
    Select Tool
    Genomic GenBank:AL935131 170938bp
    Select Tool
    Polypeptide UniProtKB:A4VCF7 (1) 678aa
    Select Tool
    Sequence Clusters UniGene:30341 (1)
    Sequence Information (all 25)
    OTHER lnx2b GENE PAGES
  • Alliance (1)
  • Gene:564464 (1)
  • VEGA:OTTDARG00000024013 (1)
  • Ensembl(GRCz11):ENSDARG00000071478 (2)
    • ORTHOLOGY for lnx2b (Chr: 14)
    CITATIONS (30)