ZFIN ID: ZDB-GENE-040426-2009
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Gene Name: ubiquitin-like modifier activating enzyme 1
Gene Symbol: uba1
Previous Names: ube1 (1), fb30f01, wu:fa01e08, wu:fb30f01, wu:fi21c11, wu:fj14g11, zgc:66143
Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66143]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  whole organism
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la011054Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa15137 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
    • sa37679 Point Mutation Unknown Unknown ENU
    sa37680 Point Mutation Unknown Unknown ENU
    Targeting reagents: MO1-uba1 (1)
    PHENOTYPE
    Data: Fig. 3 from Wishart et al., 2014
    Observed in: motor neuron axon, motor neuron collateral sprouting
    DISEASE ASSOCIATED WITH uba1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Spinal muscular atrophy, X-linked 2, infantile 301830
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axonogenesis (more)
    Cellular Component cytosol (more)
    Molecular Function ATP binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000011 (1)
  • InterPro:IPR000594 (1)
  • InterPro:IPR016040 (1)
  • InterPro:IPR018075 (1)
  • InterPro:IPR018965 (1)
  • InterPro:IPR019572 (1)
  • InterPro:IPR032418 (1)
  • InterPro:IPR032420 (1)
  • InterPro:IPR033127 (1)
    		•
  • PROSITE:PS00865 (1)
    		•
  • Pfam:PF00899 (1)
  • Pfam:PF09358 (1)
  • Pfam:PF10585 (1)
  • Pfam:PF16190 (1)
  • Pfam:PF16191 (1)
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA uba1-001 (1) 4223
    Select Tool
    uba1-002 (1) 398
    Select Tool
    uba1-003 (1) 862
    Select Tool
    ncRNA uba1-004 (1) 810
    Select Tool
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM uba1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    uba1Contained in: [BAC] CH211-112C15 (1) (order this)
    uba1Encodes: [EST] fa01e08 (1), fb30f01 (1), fi21c11 (1), fj14g11 (1)
    [cDNA] MGC:66143 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213062 (1) 4156bp
    Select Tool
    Genomic GenBank:CR339046 (1) 170974bp
    Select Tool
    Polypeptide UniProtKB:F1RCA1 (1) 1058aa
    Select Tool
    Sequence Clusters UniGene:75314 (1)
    Sequence Information (all 23)
    OTHER uba1 GENE PAGES
  • Gene:406335 (1)
  • VEGA:OTTDARG00000021287 (1)
  • Ensembl(GRCz10):ENSDARG00000037559 (1)
    • ORTHOLOGY for uba1 (Chr: 23)
    Species Symbol Chromosome Accession # Evidence
    Human UBA1 X
  • Gene:7317
  • OMIM:314370
  • HGNC:12469
    		•  Amino acid sequence comparison (1)
    Download Curated Orthology
    CITATIONS (24)