ZFIN ID: ZDB-GENE-040426-2009
Gene Name: ubiquitin-like modifier activating enzyme 1
Gene Symbol: uba1
Previous Names: ube1 (1), fb30f01, wu:fa01e08, wu:fb30f01, wu:fi21c11, wu:fj14g11, zgc:66143
Location: Chr: 23   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:66143]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  whole organism
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la011054Tg, sa15137
Knockdown reagents: MO1-uba1 (1)
PHENOTYPE
Data: Fig. 3 from Wishart et al., 2014
Observed in: motor neuron axon, motor neuron collateral sprouting

Phenotype of Human Orthologue OMIM Phenotype ID
Spinal muscular atrophy, X-linked 2, infantile 301830
GENE ONTOLOGY
Ontology GO Term
Biological Process axonogenesis (more)
Cellular Component cytosol (more)
Molecular Function ATP binding (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000011 (1)
  • InterPro:IPR000127 (1)
  • InterPro:IPR000594 (1)
  • InterPro:IPR009036 (1)
  • InterPro:IPR016040 (1)
  • InterPro:IPR018074 (1)
  • InterPro:IPR018075 (1)
  • InterPro:IPR018965 (1)
  • InterPro:IPR019572 (1)
  • InterPro:IPR023280 (1)
  • PROSITE:PS00865 (1)
  • Pfam:PF00899 (1)
  • Pfam:PF02134 (1)
  • Pfam:PF09358 (1)
  • Pfam:PF10585 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA uba1-001 (1) 4223
    uba1-002 (1) 398
    uba1-003 (1) 862
    ncRNA uba1-004 (1) 810
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM uba1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    uba1 Contained in: [BAC] CH211-112C15 (1) (order this)
    uba1 Encodes: [EST] fa01e08 (1), fb30f01 (1), fi21c11 (1), fj14g11 (1)
    [cDNA] MGC:66143 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213062 (1) 4156 bp
    Genomic GenBank:CR339046 (1) 170974 bp
    Select Tool
    Polypeptide UniProtKB:F1RCA1 (1) 1058 aa
    Sequence Clusters UniGene:75314 (1)
    Sequence Information (all 23)
    OTHER uba1 GENE PAGES
  • Gene:406335 (1)
  • VEGA:OTTDARG00000021287 (1)
  • Ensembl(Zv9):ENSDARG00000037559 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA
    Zebrafish uba1 23  
    Human UBA1 X (Xp11.23)
  • OMIM:314370
  • Gene:7317
  • Orthology Details
    CITATIONS (24)