Gene

fscn2b

ID
ZDB-GENE-040426-1740
Name
fascin actin-bundling protein 2b, retinal
Symbol
fscn2b Nomenclature History
Previous Names
  • fscn1l
  • fscn2
  • zgc:73272
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity. Predicted to be involved in actin filament bundle assembly; cell migration; and establishment or maintenance of cell polarity. Predicted to localize to actin cytoskeleton and cytoplasm. Is expressed in eye; hair cell anterior macula; otic vesicle; retina; and retinal photoreceptor layer. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 30. Orthologous to human FSCN2 (fascin actin-bundling protein 2, retinal).
Genome Resources
Note
None
Expression
All Expression Data
7 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fscn2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
retinitis pigmentosa 30 Alliance Retinitis pigmentosa 30 607921
Associated With fscn2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR022768 Fascin domain
Family IPR010431 Fascin
Family IPR024703 Fascin, metazoans
Family IPR030144 Fascin-2
Homologous_superfamily IPR008999 Actin-crosslinking
Domain Details Per Protein
Protein Length Actin-crosslinking Fascin Fascin-2 Fascin domain Fascin, metazoans
UniProtKB:Q6PBS5 290
UniProtKB:B2LT50 490
UniProtKB:F1QGR3 490
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-fscn2 polyclonal Rabbit
  • IHC
  • WB
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations