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General Information
ZIRC
ZFIN ID: ZDB-GENE-110901-1
Gene Name: fascin actin-bundling protein 2a, retinal
Gene Symbol: fscn2a    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have actin filament binding activity. Predicted to be involved in actin filament bundle assembly; cell migration; and establishment or maintenance of cell polarity. Predicted to localize to the cytoplasm. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 30. Is expressed in eye. Orthologous to human FSCN2 (fascin actin-bundling protein 2, retinal).
Genome Resources: Alliance (1),  Gene:798075 (1),  Ensembl(GRCz11):ENSDARG00000059574 (1)
GENE EXPRESSION
All Expression Data: Fig. 1 from Chou et al., 2011
Wild-type Stages, Structures: Larval:Day 4 (96.0h-120.0h) to Larval:Day 4 (96.0h-120.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-fscn2a N/A 1
MO2-fscn2a N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH fscn2a HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
retinitis pigmentosa 30 Alliance Retinitis pigmentosa 30 607921
DISEASE ASSOCIATED WITH fscn2a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process actin cytoskeleton organization (more)
Cellular Component cytoplasm (more)
Molecular Function actin binding (more)
GO Terms (all 10)
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-fscn2 polyclonal Rabbit IHC, WB 2
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM fscn2a No data available
MARKER RELATIONSHIPS No data available
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001123516 (1) 1467 bp
Genomic GenBank:CABZ01013479 (1) 12105 bp
Polypeptide UniProtKB:B2LT49 (1) 488 aa
Sequence Clusters UniGene:139451 (1)
Sequence Information (all 12)
ORTHOLOGY for fscn2a ( Chr: 3 )
CITATIONS (15)