Gene

fscn2a

ID
ZDB-GENE-110901-1
Name
fascin actin-bundling protein 2a, retinal
Symbol
fscn2a Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity. Predicted to be involved in actin filament bundle assembly; cell migration; and establishment or maintenance of cell polarity. Predicted to localize to actin cytoskeleton and cytoplasm. Is expressed in eye. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 30. Orthologous to human FSCN2 (fascin actin-bundling protein 2, retinal).
Genome Resources
Note
None
Expression
All Expression Data
from Chou et al., 2011
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fscn2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
retinitis pigmentosa 30 Alliance Retinitis pigmentosa 30 607921
Associated With fscn2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR022768 Fascin domain
Family IPR010431 Fascin
Family IPR024703 Fascin, metazoans
Family IPR030144 Fascin-2
Homologous_superfamily IPR008999 Actin-crosslinking
Domain Details Per Protein
Protein Length Actin-crosslinking Fascin Fascin-2 Fascin domain Fascin, metazoans
UniProtKB:F1QK37 488
UniProtKB:B2LT49 488
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-fscn2 polyclonal Rabbit
  • IHC
  • WB
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations