Gene
fscn2a
- ID
- ZDB-GENE-110901-1
- Name
- fascin actin-bundling protein 2a, retinal
- Symbol
- fscn2a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have actin filament binding activity. Predicted to be involved in actin filament bundle assembly; cell migration; and establishment or maintenance of cell polarity. Predicted to localize to actin cytoskeleton and cytoplasm. Is expressed in eye. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 30. Orthologous to human FSCN2 (fascin actin-bundling protein 2, retinal).
- Genome Resources
- Note
- None
- All Expression Data
- from Chou et al., 2011
- Cross-Species Comparison
- High Throughput Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| retinitis pigmentosa 30 | Alliance | Retinitis pigmentosa 30 | 607921 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Actin-crosslinking | Fascin | Fascin-2 | Fascin domain | Fascin, metazoans |
|---|---|---|---|---|---|---|
|
UniProtKB:F1QK37
|
488 | |||||
|
UniProtKB:B2LT49
|
488 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available