| ZFIN ID: ZDB-GENE-110901-1 |
| Gene Name: | fascin actin-bundling protein 2a, retinal | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gene Symbol: | fscn2a Nomenclature History |
{{control.fieldName}} Edit
Attributions
|
||||||||||||
| Previous Name: | ||||||||||||||
Add new Alias
Attributions for Alias: {{control.newAlias}}
Delete Alias:(Including Attributions) |
||||||||||||||
| Gene Type: | protein_coding_gene | |||||||||||||
| Location: | Chr: 3 Mapping Details/Browsers | |||||||||||||
| Description: | Predicted to have actin filament binding activity. Predicted to be involved in actin filament bundle assembly; cell migration; and establishment or maintenance of cell polarity. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 30. Is expressed in eye. Orthologous to human FSCN2 (fascin actin-bundling protein 2, retinal). | |||||||||||||
| Genome Resources: | Alliance (1), Gene:798075 (1), Ensembl(GRCz11):ENSDARG00000059574 (1) | |||||||||||||
| All Expression Data: | Fig. 1 from Chou et al., 2011 |
| Wild-type Stages, Structures: | Larval:Day 4 (96.0h-120.0h) to Larval:Day 4 (96.0h-120.0h) |
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
| Targeting Reagent | Created Alleles | Publications |
|---|---|---|
| MO1-fscn2a | N/A | 1 |
| MO2-fscn2a | N/A | 1 |
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| retinitis pigmentosa 30 | Alliance | Retinitis pigmentosa 30 | 607921 |
GENE ONTOLOGY
| Ontology | GO Term |
|---|---|
| Biological Process | actin cytoskeleton organization (more) |
| Cellular Component | cytoplasm (more) |
| Molecular Function | actin binding (more) |
TRANSCRIPTS No data available
INTERACTIONS AND PATHWAYS
ANTIBODIES
| Name | Type | Isotype | Host Organism | Assay | Source | Publications |
|---|---|---|---|---|---|---|
| Ab1-fscn2 | polyclonal | Rabbit | IHC, WB | 2 |
PLASMIDS
No data available
CONSTRUCTS WITH SEQUENCES FROM fscn2a
No data available
MARKER RELATIONSHIPS
No data available
SEQUENCE INFORMATION
| Type | Accession # | Length (nt/aa) | Analysis |
|---|---|---|---|
| RNA | RefSeq:NM_001123516 (1) | 1467 nt |
Select Tool
|
| Genomic | GenBank:CABZ01013479 (1) | 12105 nt |
Select Tool
|
| Polypeptide | UniProtKB:B2LT49 (1) | 488 aa |
Select Tool
|
ORTHOLOGY for fscn2a (
Chr:
3
)
CITATIONS (16)