ZFIN ID: ZDB-GENE-040426-1040
Gene Name: F-box protein 32
Gene Symbol: fbxo32    Nomenclature History

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Previous Names: atrogin-1 (1), atrogin1 (1), zgc:56479 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Involved in several processes, including cardiac muscle tissue morphogenesis; larval locomotory behavior; and muscle cell cellular homeostasis. Localizes to cytoplasm. Is expressed in cardiac muscle cell; muscle; skeletal muscle cell; and yolk syncytial layer. Orthologous to human FBXO32 (F-box protein 32).
Genome Resources: Alliance (1),  Gene:393891 (1),  Ensembl(GRCz11):ENSDARG00000040277 (2)
GENE EXPRESSION
All Expression Data: 10 figures from 6 publications
Directly Submitted Expression Data: 3 figures (3 images) from Thisse et al., 2004 [MGC:56479]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027713Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa6431 Point Mutation Unknown Premature Stop ENU
    sa8703 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa9611 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-fbxo32 N/A 1
    MO2-fbxo32 N/A 1
    MO3-fbxo32 N/A 1
    MO4-fbxo32 N/A 1
    DISEASE ASSOCIATED WITH fbxo32 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH fbxo32 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process autophagy (more)
    Cellular Component cytoplasm (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA fbxo32-201 (1)    Ensembl 1752
    ncRNA fbxo32-002 (1)    Ensembl 607
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-fbxo32 polyclonal Rabbit IHC ECM Biosciences LLC
    2
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fbxo32 No data available
    MARKER RELATIONSHIPS
    fbxo32 Contained in: [BAC] DKEY-29H14 (1) (order this)
    fbxo32 Encodes: [cDNA] MGC:56479 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200917 (1) 1804 nt
    Genomic GenBank:BX571853 (1) 191052 nt
    Select Tool
    Polypeptide UniProtKB:F1R1Z0 (1) 356 aa
    Sequence Information (all 9)
    ORTHOLOGY for fbxo32 ( Chr: 16 )
    CITATIONS (37)