ZFIN ID: ZDB-GENE-031001-2
Gene Name: tight junction protein 1a
Gene Symbol: tjp1a
Sequence Ontology ID : SO:0000704

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Previous Names: tjp1.1 (1), tjp1, zo-1 (1), cb817 (1)

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(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 43 figures from 22 publications
Directly Submitted Expression Data: 5 figures (9 images) from Thisse et al., 2001 [cb817]
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Larval:Day 4 (96.0h-120.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
fh463 Small Deletion Unknown Unknown CRISPR
sa7069 Point Mutation Unknown Premature Stop ENU
sa13285 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20982 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34097 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40924 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tnh009b Point Mutation Unknown Premature Stop ENU
    twc2 Point Mutation Unknown Premature Stop ENU
    twl1 Point Mutation Unknown Premature Stop ENU
    twl4 Point Mutation Unknown Premature Stop ENU
    twlc19 Point Mutation Unknown Premature Stop ENU
    Targeting reagents:
    PHENOTYPE
    Data: 5 figures from Fadeev et al., 2015
    Observed in:
    DISEASE ASSOCIATED WITH tjp1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tjp1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process pigmentation (more)
    Cellular Component bicellular tight junction (more)
    Molecular Function protein binding (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000906 (1)
  • InterPro:IPR001452 (1)
  • InterPro:IPR001478 (1)
  • InterPro:IPR005417 (1)
  • InterPro:IPR005418 (1)
  • InterPro:IPR008144 (1)
  • InterPro:IPR008145 (1)
  • InterPro:IPR027417 (1)
  • InterPro:IPR035597 (1)
  • InterPro:IPR036028 (1)
  • InterPro:IPR036034 (1)
  • PROSITE:PS50002 (1)
  • PROSITE:PS50052 (1)
  • PROSITE:PS50106 (1)
  • PROSITE:PS51145 (1)
  • Pfam:PF00595 (1)
  • Pfam:PF00625 (1)
  • Pfam:PF00791 (1)
  • Pfam:PF07653 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tjp1a-001 (1) 6999
    tjp1a-002 (1) 676
    tjp1a-003 (1) 612
    ncRNA tjp1a-004 (1) 751
    mRNA tjp1a-005 (1) 485
    tjp1a-006 (1) 784
    tjp1a-007 (1) 544
    tjp1a-008 (1) 206
    tjp1a-009 (1) 1035
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tjp1a
    MARKER RELATIONSHIPS
    tjp1aContained in: [BAC] DKEY-1H4 (1) (order this)
    tjp1aEncodes: [EST] cb817 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005168933 (1) 7284bp
    Genomic GenBank:BX649429 (1) 268480bp Blast at MegaBLAST
    Polypeptide UniProtKB:A0A2R8QMK9 (1) 1689aa
    Sequence Clusters UniGene:160253 (1)
    Sequence Information (all 53)
    OTHER tjp1a GENE PAGES
  • Alliance (1)
  • Gene:378845 (1)
  • VEGA:OTTDARG00000029763 (1)
  • Ensembl(GRCz11):ENSDARG00000077506 (2)
  • ORTHOLOGY for tjp1a (Chr: 7)
    CITATIONS (54)