Gene

atp6v1ba

ID
ZDB-GENE-030711-3
Name
ATPase, H+ transporting, lysosomal, V1 subunit B, member a
Symbol
atp6v1ba Nomenclature History
Previous Names
  • vatB1 (1)
  • cb927 (1)
  • fb52g11
  • wu:fb52g11 (1)
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have ATP binding activity. Predicted to be involved in ATP metabolic process and proton transmembrane transport. Predicted to localize to proton-transporting V-type ATPase, V1 domain. Is expressed in several structures, including mucus secreting cell; nervous system; notochord; polster; and yolk syncytial layer. Human ortholog(s) of this gene implicated in autosomal dominant congenital deafness with onychodystrophy. Orthologous to human ATP6V1B2 (ATPase H+ transporting V1 subunit B2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With atp6v1ba Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant congenital deafness with onychodystrophy Alliance Deafness, congenital, with onychodystrophy, autosomal dominant 124480
Zimmermann-Laband syndrome 2 616455
Associated With atp6v1ba Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site
Domain IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain
Domain IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain
Family IPR005723 ATPase, V1 complex, subunit B
Family IPR022879 V-type ATP synthase regulatory subunit B/beta
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length ATPase, alpha/beta subunit, nucleotide-binding domain, active site ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain ATPase, V1 complex, subunit B P-loop containing nucleoside triphosphate hydrolase V-type ATP synthase regulatory subunit B/beta
UniProtKB:Q8QHA7 506
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA atp6v1ba-201 (1) Ensembl 2,547 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations