ZFIN ID: ZDB-GENE-030519-2
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Gene Name: neuropilin 1a
Gene Symbol: nrp1a
Sequence Ontology ID : SO:0000704

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Previous Names: np-1, npn-1A (1), nrp1, znrp1, zgc:111785 (1), zgc:136674 (1)

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(Including Attributions)
Location: Chr: 24 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits vascular endothelial growth factor-activated receptor activity; involved in several processes, including animal organ development, blood vessel morphogenesis, and generation of neurons;  ...
GENE EXPRESSION
All Expression Data: 27 figures from 23 publications
Wild-type Stages, Structures: Segmentation:5-9 somites (11.66h-14.0h) to Larval:Day 4 (96.0h-120.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu9963 Small Deletion Unknown Frameshift, Premature Stop TALEN
hu10012 Small Deletion Unknown Frameshift, Premature Stop TALEN
la028593Tg Transgenic Insertion Unknown Unknown DNA
sa32 Point Mutation Unknown Missense ENU
  • European Zebrafish Resource Center (EZRC) (order this)
    • sa33 Point Mutation Unknown Unknown ENU
    sa34 Point Mutation Unknown Unknown ENU
    sa1485 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa24429 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa24430 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • sa37806 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • Targeting reagents:
    PHENOTYPE
    Data: 11 figures from 10 publications
    Observed in:
    DISEASE ASSOCIATED WITH nrp1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nrp1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to hypoxia (more)
    Cellular Component integral component of membrane (more)
    Molecular Function vascular endothelial growth factor-activated receptor activity (more)
    GO Terms (all 33)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000421 (1)
  • InterPro:IPR000859 (1)
  • InterPro:IPR000998 (1)
  • InterPro:IPR008979 (1)
  • InterPro:IPR013320 (1)
  • InterPro:IPR014648 (1)
  • InterPro:IPR022579 (1)
  • InterPro:IPR027146 (1)
  • InterPro:IPR035914 (1)
    		•
  • PROSITE:PS00740 (1)
  • PROSITE:PS01180 (1)
  • PROSITE:PS01285 (1)
  • PROSITE:PS01286 (1)
  • PROSITE:PS50022 (1)
  • PROSITE:PS50060 (1)
    		•
  • Pfam:PF00431 (1)
  • Pfam:PF00629 (1)
  • Pfam:PF00754 (1)
  • Pfam:PF11980 (1)
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA nrp1a-201 (1) 3875
    Select Tool
    nrp1a-202 (1) 3644
    Select Tool
    nrp1a-203 (1) 1977
    Select Tool
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM nrp1a
    MARKER RELATIONSHIPS
    nrp1aContained in: [BAC] CH73-134F24 (1) (order this), DKEY-97G1 (1) (order this), DKEYP-9D12 (1), RP71-26B20 (1) (order this)
    nrp1aEncodes: [cDNA] MGC:111785 (order this), MGC:136674 (1) (order this), MGC:195315 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001040326 (1) 3901bp
    Select Tool
    Genomic GenBank:BX323074 (1) 153860bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IFP8 (1) 926aa
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    Sequence Clusters UniGene:133652 (1)
    Sequence Information (all 46)
    OTHER nrp1a GENE PAGES
  • Alliance (1)
  • Gene:353246 (1)
  • VEGA:OTTDARG00000036481 (1)
  • Ensembl(GRCz11):ENSDARG00000102153 (1)
    • ORTHOLOGY for nrp1a (Chr: 24)
    CITATIONS (84)